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Completed Phase 3 Interventional Accepts healthy volunteers Results available

Study of MK-4482 for Prevention of Coronavirus Disease 2019 (COVID-19) in Adults (MK-4482-013)

ClinicalTrials.gov ID: NCT04939428

Public ClinicalTrials.gov record NCT04939428. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 6:14 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of MK-4482 for the Prevention of COVID-19 (Laboratory-confirmed SARS-CoV-2 Infection With Symptoms) in Adults Residing With a Person With COVID-19

Study identification

NCT ID
NCT04939428
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
2,441 participants

Conditions and interventions

Interventions

  • Molnupiravir Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 10, 2021
Primary completion
Nov 15, 2022
Completion
Nov 15, 2022
Last update posted
Sep 25, 2024

2021 – 2022

United States locations

U.S. sites
59
U.S. states
29
U.S. cities
56
Facility City State ZIP Site status
Cahaba Research, Inc. ( Site 2523) Birmingham Alabama 35235
The Institute for Liver Health DBA Arizona Clinical Trials ( Site 2484) Mesa Arizona 85210
The Institute for Liver Health DBA Arizona Clinical Trials ( Site 2448) Tucson Arizona 85712
Hope Clinical Research ( Site 2400) Canoga Park California 91303
Carbon Health ( Site 2515) Carlsbad California 92009
UCSF Fresno ( Site 2528) Fresno California 93701
ASCADA Research, LLC ( Site 2516) Fullerton California 92835
Marvel Clinical Research ( Site 2490) Huntington Beach California 92647
National Research Institute ( Site 2452) Los Angeles California 90057
Valley Clinical Trials Inc. ( Site 2406) Northridge California 91325
Carbon Health ( Site 2514) Oakland California 94610
University of California Davis ( Site 2497) Sacramento California 95817
Millennium Clinical Trials ( Site 2468) Simi Valley California 93065
Future Innovative Treatments, LLC ( Site 2471) Colorado Springs Colorado 80907
Emerson Clinical Research Institute ( Site 2457) Washington D.C. District of Columbia 20011
Synergy Healthcare ( Site 2521) Bradenton Florida 34208
Accel Research Sites-DeLand Clinical Research Unit ( Site 2535) DeLand Florida 32720
Velocity Clinical Research, Hallandale Beach ( Site 2485) Hallandale Florida 33009
Indago Research and Health Center Inc ( Site 2412) Hialeah Florida 33012
Advanced Research For Health Improvement LLC ( Site 2436) Immokalee Florida 34142
Clinical Site Partners, LLC d/b/a CSP Miami ( Site 2508) Miami Florida 33186
CDC Research Institute, LLC ( Site 2540) Port Saint Lucie Florida 34952
Clinical Research Trials of Florida ( Site 2402) Tampa Florida 33607
Clinical Site Partners, LLC d/b/a CSP Miami ( Site 2425) Winter Park Florida 32789
Balanced Life Healthcare Solutions/SKYCRNG ( Site 2539) Lawrenceville Georgia 30046
Chicago Clinical Research Institute Inc ( Site 2454) Chicago Illinois 60607
Rush University Medical Center ( Site 2510) Chicago Illinois 60612
Southern Clinical Research Associates ( Site 2542) Metairie Louisiana 70001
MedPharmics, LLC ( Site 2443) Metairie Louisiana 70006
Institute of Human Virology ( Site 2504) Baltimore Maryland 21201
Centennial Medical Group ( Site 2435) Elkridge Maryland 21075
Jadestone Clinical Research, LLC ( Site 2530) Silver Spring Maryland 20904
Michigan Center of Medical Research ( Site 2445) Farmington Hills Michigan 48334
Michigan Center of Medical Research ( Site 2525) Lathrup Village Michigan 48076
Allina Health Infectious Diseases Research Clinic ( Site 2507) Minneapolis Minnesota 55404
Prime Health and Wellness/SKYCRNG ( Site 2538) Fayette Mississippi 39069
Quinn Healthcare/Skycrng ( Site 2537) Ridgeland Mississippi 39157
University of Missouri Hospital ( Site 2486) Columbia Missouri 65201
Mercury Street Medical Group PLLC ( Site 2476) Butte Montana 59701
University of Nebraska Medical Center ( Site 2430) Omaha Nebraska 68198-3135
Excel Clinical Research, LLC ( Site 2404) Las Vegas Nevada 89109
ID Care ( Site 2466) Hillsborough New Jersey 08844
Amici Clinical Research LLC ( Site 2426) Raritan New Jersey 08869
AXCES Research Group ( Site 2437) Santa Fe New Mexico 87505
Montefiore Medical Center ( Site 2503) The Bronx New York 10462
ECU Adult Specialty Care ( Site 2415) Greenville North Carolina 27834
The Lindner Center for Research and Education at The Christ Hospital ( Site 2517) Cincinnati Ohio 45219
Dayton Clinical Research ( Site 2488) Dayton Ohio 45406
Cherokee Nation WW Hastings Indian Hospital/Cherokee Nation Health Services ( Site 2459) Tahlequah Oklahoma 74464
Preferred Clinical Research ( Site 2470) Pittsburgh Pennsylvania 15236
Velocity Clinical Research-Providence ( Site 2432) East Greenwich Rhode Island 02818
Tribe Clinical Research, LLC ( Site 2409) Greenville South Carolina 29607
PharmaTex Research, LLC ( Site 2541) Amarillo Texas 79109
TTS Research ( Site 2433) Boerne Texas 78006
Houston Methodist Hospital ( Site 2463) Houston Texas 77030
Santa Clara Family Clinic ( Site 2462) Houston Texas 77087
Crossroads Clinical Research LLC ( Site 2451) Victoria Texas 77901
TPMG Clinical Research ( Site 2495) Williamsburg Virginia 23188
Covid-19 Clinical Research Center (CCRC) ( Site 2421) Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 167 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04939428, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 25, 2024 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04939428 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →