A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)
Public ClinicalTrials.gov record NCT04944784. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the effect of reldesemtiv versus placebo on functional outcomes in ALS.
Study identification
- NCT ID
- NCT04944784
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 489 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 15, 2021
- Primary completion
- Jul 17, 2023
- Completion
- Jul 17, 2023
- Last update posted
- Dec 4, 2024
2021 – 2023
United States locations
- U.S. sites
- 36
- U.S. states
- 24
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Joseph's Hospital & Medical Center - Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California Irvine - ALS & Neuromuscular Center | Orange | California | 92868 | — |
| California Pacific Medical Center - Forbes Norris MDA/ALS Research Center | San Francisco | California | 94109 | — |
| Stanford Hospital and Clinics | Stanford | California | 94305 | — |
| University of Colorado Hospital Anschutz Outpatient Pavilion | Aurora | Colorado | 80045 | — |
| GW Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | — |
| University of Florida Jacksonville | Jacksonville | Florida | 32209 | — |
| Mayo Clinic Florida | Jacksonville | Florida | 32224 | — |
| University of South Florida - Carol and Frank Morsani Center for Advanced Health Care | Tampa | Florida | 33612 | — |
| Duchossois Center for Advanced Medicine | Chicago | Illinois | 60637 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| The University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Johns Hopkins Outpatient Center | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital - Neurological Clinical Research Institute | Boston | Massachusetts | 02114 | — |
| University of Massachusetts Memorial Medical Center/Medical School | Worcester | Massachusetts | 01655 | — |
| Michigan Medicine | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Washington University School of Medicine - Center for Advance Medicine | St Louis | Missouri | 63108 | — |
| Neurology Associates, PC | Lincoln | Nebraska | 68506 | — |
| Hospital for Special Surgery | New York | New York | 10021 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Atrium Health Neuroscience Institute - Charlotte | Charlotte | North Carolina | 28207 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Providence ALS Center | Portland | Oregon | 97213 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Penn State Health Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Lewis Katz School of Medicine at Temple University | Philadelphia | Pennsylvania | 19140 | — |
| Vanderbilt University Medical Center - Clinical Research Center | Nashville | Tennessee | 37232 | — |
| Texas Neurology, P.A. | Dallas | Texas | 75206 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| VCU Neuroscience Orthopaedic and Wellness Center (NOW) | Henrico | Virginia | 23233 | — |
| Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04944784, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 4, 2024 · Synced Sep 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04944784 live on ClinicalTrials.gov.