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Completed Phase 1 Interventional Accepts healthy volunteers

Phase 1 Study of Intranasal PIV5 COVID-19 Vaccine Expressing SARS-CoV-2 Spike Protein in Healthy Adults and Adolescents

ClinicalTrials.gov ID: NCT04954287

Public ClinicalTrials.gov record NCT04954287. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 4:44 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Open-Label, Dose-Ranging Trial to Evaluate the Safety and Immunogenicity of Intranasal Parainfluenza Virus Type 5- SARS CoV-2 S Vaccine (CVXGA1) in Healthy Adults Aged 18 to 55 Years and Adolescents Aged 12 to 17 Years

Study identification

NCT ID
NCT04954287
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
CyanVac LLC
Industry
Enrollment
72 participants

Conditions and interventions

Conditions

Interventions

  • CVXGA1 low dose Biological
  • CVXGA1 high dose Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 55 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 5, 2021
Primary completion
Jun 9, 2023
Completion
Jun 9, 2023
Last update posted
Feb 6, 2024

2021 – 2023

United States locations

U.S. sites
4
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
Kentucky Pediatric/ Adult Research Bardstown Kentucky 40004
University of Rochester Medical Center Rochester New York 14642
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229
Research Your Health Plano Texas 75093

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04954287, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 6, 2024 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04954287 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →