Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENT®) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Public ClinicalTrials.gov record NCT04959448. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Assessing Long-Term Outcomes of DUPIXENT® Treatment in Patients With Chronic Rhinosinusitis With Nasal Polyposis (AROMA)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objectives of the study are: * To longitudinally characterize the long-term effectiveness of DUPIXENT® through assessment of patient-reported symptoms, Health-Related Quality of Life (HRQoL) related to Chronic rhinosinusitis with nasal polyposis (CRSwNP) and other type 2 comorbidities, and their change over-time. * To characterize patients who receive DUPIXENT® for CRSwNP in a real-world setting with respect to their medical history, demographic and disease characteristics, and type 2 comorbidities The secondary objectives of the study are: * To characterize real-world utilization of DUPIXENT® for patients with CRSwNP * To collect patient and physician global assessment of disease severity and treatment satisfaction for patients receiving DUPIXENT® for CRSwNP * To collect long-term safety data for patients receiving DUPIXENT® for CRSwNP
Study identification
- NCT ID
- NCT04959448
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 717 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 12, 2021 (Actual)
- Primary completion
- Mar 25, 2027 (Estimated)
- Completion
- Mar 25, 2027 (Estimated)
- Last update posted
- Jul 13, 2026
2021 – 2027
United States locations
- U.S. sites
- 48
- U.S. states
- 26
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Excel ENT of Alabama | Birmingham | Alabama | 35244 | — |
| Medical Research of Arizona, a division of Allergy, Asthma & Immunology Associates | Scottsdale | Arizona | 85251 | — |
| The Allergy and Rheumatology Medical Clinic | La Jolla | California | 92037 | — |
| ARK Clinical Research | Long Beach | California | 90806 | — |
| Scripps Health - Scripps Clinic Carmel Valley | San Diego | California | 92130 | — |
| Breathe Clear Institute | Torrance | California | 90503 | — |
| Allergy & Asthma Clinical Research | Walnut Creek | California | 94598 | — |
| AADRS Clincial Research Center | Coral Gables | Florida | 33134 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Damask Physicians Group | Lake Mary | Florida | 32746 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| IACT Health | Columbus | Georgia | 31904 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | — |
| Northwestern University Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| The University of Chicago Medical Center UCMC Duchossois Center for Advanced Medicine DCAM | Chicago | Illinois | 60637 | — |
| Asthma & Allergy Center of Chicago | Oak Park | Illinois | 60301 | — |
| Indiana University Health | Indianapolis | Indiana | 46202 | — |
| John Hopkins University School Of Medicine | Baltimore | Maryland | 21224 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan, Michigan Medicine Pulmonary Clinic | Ann Arbor | Michigan | 48109-5000 | — |
| Allergy & Asthma Center of Minnesota - Allergology | Maplewood | Minnesota | 55109 | — |
| University of Missouri | Columbia | Missouri | 65212 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Atlantic Research Center LLC | Ocean City | New Jersey | 07712 | — |
| Northwell Health | Great Neck | New York | 11021 | — |
| Montefiore Medical Center | New York | New York | 10461 | — |
| Rochester Regional Health System | Rochester | New York | 14626 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Allergy Partners of the Triangle | Raleigh | North Carolina | 27607 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati College of Medicine | Cincinnati | Ohio | 45229 | — |
| Essential Medical Research | Tulsa | Oklahoma | 74137 | — |
| Asthma, Nasal Disease & Allergy Research Center of New England | East Providence | Rhode Island | 02914 | — |
| Allergy and Asthma Physicians of RI | Lincoln | Rhode Island | 02865 | — |
| Medical University Of South Carolina | Charleston | South Carolina | 29425 | — |
| ADAC research, PA | Greenville | South Carolina | 29607 | — |
| Spartanburg Ear, Nose & Throat Clinical | Spartanburg | South Carolina | 29303 | — |
| ENT & Allergy Partners | Summerville | South Carolina | 29486 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| STAAMP Research | San Antonio | Texas | 78229 | — |
| Tanner Clinic | Layton | Utah | 84041 | — |
| University of Virginia Health System (UVA) | Charlottesville | Virginia | 22903 | — |
| Eastern Virginia Medical School | Norfolk | Virginia | 23510 | — |
| Richmond Ear Nose & Throat | Richmond | Virginia | 23235 | — |
| The Vancouver Clinic | Vancouver | Washington | 98664 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 33 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04959448, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 13, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04959448 live on ClinicalTrials.gov.