ClinicalTrials.gov record
Completed Phase 2Phase 3 Interventional Results available

EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19

ClinicalTrials.gov ID: NCT04960202

Public ClinicalTrials.gov record NCT04960202. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 5, 2026, 7:06 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

AN INTERVENTIONAL EFFICACY AND SAFETY, PHASE 2/3, DOUBLE-BLIND, 2-ARM STUDY TO INVESTIGATE ORALLY ADMINISTERED PF-07321332/RITONAVIR COMPARED WITH PLACEBO IN NONHOSPITALIZED SYMPTOMATIC ADULT PARTICIPANTS WITH COVID-19 WHO ARE AT INCREASED RISK OF PROGRESSING TO SEVERE ILLNESS

Study identification

NCT ID
NCT04960202
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
2,091 participants

Conditions and interventions

Conditions

Interventions

  • PF-07321332 Drug
  • Placebo Drug
  • Ritonavir Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 15, 2021
Primary completion
Dec 8, 2021
Completion
Apr 24, 2022
Last update posted
Jul 9, 2025

2021 – 2022

United States locations

U.S. sites
73
U.S. states
14
U.S. cities
49
Facility City State ZIP Site status
Cahaba Research Inc Pelham Alabama 35124
The Institute for Liver Health dba Arizona Clinical Trials Mesa Arizona 85210
The Institute for Liver Health dba Arizona Clinical Trials Tucson Arizona 85712
Hope Clinical Research Canoga Park California 91303
Ascada Research Fullerton California 92835
Atella Clinical Research LLC. La Palma California 90623
Ark Clinical Research Long Beach California 90806
American Institute of Research Los Angeles California 90017
South Bay Clinical Research Institute Redondo Beach California 90277
Hope Clinical Research (COVID Satellite Site) West Hills California 91304
Future Innovative Treatments, LLC Colorado Springs Colorado 80907
Xera Med Research Boca Raton Florida 33487
MOORE Clinical Research, Inc. Brandon Florida 33511
Innovative Research of West Florida, Inc. Clearwater Florida 33756
Herco Medical and Research Center Inc Coral Gables Florida 33134
Advance Clinical Research Group Cutler Bay Florida 33157
Beautiful Minds Clinical Research Center Cutler Bay Florida 33157
Qway Research Hialeah Florida 33010
Eastern Research Inc Hialeah Florida 33013
Inpatient Research Clinic Hialeah Florida 33013
Doral Medical Research LLC. Hialeah Florida 33016
Doral Medical Research,LLC Hialeah Florida 33016
Unlimited Medical Research Group, LLC Hialeah Gardens Florida 33018
Advanced Pulmonary Research Institute Loxahatchee Groves Florida 33470
Angels Clinical Research Institute Miami Florida 33122
LCC Medical Research Institute, LLC Miami Florida 33126
Premium Medical Research Corp Miami Florida 33126
Global Health Clinical Trials Corp Miami Florida 33135
South Florida Research Center, Inc. Miami Florida 33135
Suncoast Research Group, LLC Miami Florida 33135
I.V.A.M. Clinical & Investigational Center, LLC Miami Florida 33144
C'A Research Miami Florida 33174
ProLive Medical Research, Corp. Miami Florida 33175
Entrust Clinical Research Miami Florida 33176
Reed Medical Research Miami Florida 33176
Kendall South Medical Center Miami Florida 33185
Clinical Site Partners, Inc d/b/a CSP Miami Miami Florida 33186
Coral Research Clinic Corp Miami Florida 33186
Savin Medical Group, LLC Miami Lakes Florida 33014
Omega Research Orlando, LLC Orlando Florida 32808
NAPA Research LLC Pompano Beach Florida 33064
CDC Research Institute Port Saint Lucie Florida 34952
USPA Advance Concept Medical Research Group LLC South Miami Florida 33143
GCP, Global Clinical Professionals St. Petersburg Florida 33705
Sunrise Research Institute Sunrise Florida 33325
Santos Research Center, CORP Tampa Florida 33615
Clinical Site Partners, Inc. dba CSP Orlando Winter Park Florida 32789
Research by Design, LLC Chicago Illinois 60643
New Orleans Sinus Center (COVID-19 Testing) Marrero Louisiana 70072
Tandem Clinical Research GI, LLC Marrero Louisiana 70072
Mercury Street Medical Group, PLLC Butte Montana 59701
Excel Clinical research Las Vegas Nevada 89109
Meridian Clinical Research, LLC Endwell New York 13760
Monroe Biomedical Research Monroe North Carolina 28112
Accellacare Wilmington North Carolina 28401
Premier Medical Group Clarksville Tennessee 37040
PharmaTex Research, LLC Amarillo Texas 79109
ARC Clinical Research at William Cannon Austin Texas 78745
St Hope Foundation Bellaire Texas 77401
Conroe Willis Medical Research Conroe Texas 77304
South Texas Clinical Research Corpus Christi Texas 78413
SignatureCare Emergency Center Houston Texas 77008
Trio Clinical Trials, LLC Houston Texas 77008
C & R Research Services USA Houston Texas 77022
Next Level Urgent Care Houston Texas 77057
SMS Clinical Research, LLC Mesquite Texas 75149
SMS Clinical Research Mesquite Texas 75149
LinQ Research, LLC Pearland Texas 77584
Epic Medical Research Red Oak Texas 75154
Sun Research Institute San Antonio Texas 78215
BFHC Research San Antonio Texas 78249
Tranquility Research Webster Texas 77598
TPMG (Tidewater Physicians Multispecialty Group) Clinical Research Newport News Virginia 23606

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 128 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04960202, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 9, 2025 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04960202 live on ClinicalTrials.gov.

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