EPIC-HR: Study of Oral PF-07321332/Ritonavir Compared With Placebo in Nonhospitalized High Risk Adults With COVID-19
Public ClinicalTrials.gov record NCT04960202. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
AN INTERVENTIONAL EFFICACY AND SAFETY, PHASE 2/3, DOUBLE-BLIND, 2-ARM STUDY TO INVESTIGATE ORALLY ADMINISTERED PF-07321332/RITONAVIR COMPARED WITH PLACEBO IN NONHOSPITALIZED SYMPTOMATIC ADULT PARTICIPANTS WITH COVID-19 WHO ARE AT INCREASED RISK OF PROGRESSING TO SEVERE ILLNESS
Study identification
- NCT ID
- NCT04960202
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 2,091 participants
Conditions and interventions
Conditions
Interventions
- PF-07321332 Drug
- Placebo Drug
- Ritonavir Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 15, 2021
- Primary completion
- Dec 8, 2021
- Completion
- Apr 24, 2022
- Last update posted
- Jul 9, 2025
2021 – 2022
United States locations
- U.S. sites
- 73
- U.S. states
- 14
- U.S. cities
- 49
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Research Inc | Pelham | Alabama | 35124 | — |
| The Institute for Liver Health dba Arizona Clinical Trials | Mesa | Arizona | 85210 | — |
| The Institute for Liver Health dba Arizona Clinical Trials | Tucson | Arizona | 85712 | — |
| Hope Clinical Research | Canoga Park | California | 91303 | — |
| Ascada Research | Fullerton | California | 92835 | — |
| Atella Clinical Research LLC. | La Palma | California | 90623 | — |
| Ark Clinical Research | Long Beach | California | 90806 | — |
| American Institute of Research | Los Angeles | California | 90017 | — |
| South Bay Clinical Research Institute | Redondo Beach | California | 90277 | — |
| Hope Clinical Research (COVID Satellite Site) | West Hills | California | 91304 | — |
| Future Innovative Treatments, LLC | Colorado Springs | Colorado | 80907 | — |
| Xera Med Research | Boca Raton | Florida | 33487 | — |
| MOORE Clinical Research, Inc. | Brandon | Florida | 33511 | — |
| Innovative Research of West Florida, Inc. | Clearwater | Florida | 33756 | — |
| Herco Medical and Research Center Inc | Coral Gables | Florida | 33134 | — |
| Advance Clinical Research Group | Cutler Bay | Florida | 33157 | — |
| Beautiful Minds Clinical Research Center | Cutler Bay | Florida | 33157 | — |
| Qway Research | Hialeah | Florida | 33010 | — |
| Eastern Research Inc | Hialeah | Florida | 33013 | — |
| Inpatient Research Clinic | Hialeah | Florida | 33013 | — |
| Doral Medical Research LLC. | Hialeah | Florida | 33016 | — |
| Doral Medical Research,LLC | Hialeah | Florida | 33016 | — |
| Unlimited Medical Research Group, LLC | Hialeah Gardens | Florida | 33018 | — |
| Advanced Pulmonary Research Institute | Loxahatchee Groves | Florida | 33470 | — |
| Angels Clinical Research Institute | Miami | Florida | 33122 | — |
| LCC Medical Research Institute, LLC | Miami | Florida | 33126 | — |
| Premium Medical Research Corp | Miami | Florida | 33126 | — |
| Global Health Clinical Trials Corp | Miami | Florida | 33135 | — |
| South Florida Research Center, Inc. | Miami | Florida | 33135 | — |
| Suncoast Research Group, LLC | Miami | Florida | 33135 | — |
| I.V.A.M. Clinical & Investigational Center, LLC | Miami | Florida | 33144 | — |
| C'A Research | Miami | Florida | 33174 | — |
| ProLive Medical Research, Corp. | Miami | Florida | 33175 | — |
| Entrust Clinical Research | Miami | Florida | 33176 | — |
| Reed Medical Research | Miami | Florida | 33176 | — |
| Kendall South Medical Center | Miami | Florida | 33185 | — |
| Clinical Site Partners, Inc d/b/a CSP Miami | Miami | Florida | 33186 | — |
| Coral Research Clinic Corp | Miami | Florida | 33186 | — |
| Savin Medical Group, LLC | Miami Lakes | Florida | 33014 | — |
| Omega Research Orlando, LLC | Orlando | Florida | 32808 | — |
| NAPA Research LLC | Pompano Beach | Florida | 33064 | — |
| CDC Research Institute | Port Saint Lucie | Florida | 34952 | — |
| USPA Advance Concept Medical Research Group LLC | South Miami | Florida | 33143 | — |
| GCP, Global Clinical Professionals | St. Petersburg | Florida | 33705 | — |
| Sunrise Research Institute | Sunrise | Florida | 33325 | — |
| Santos Research Center, CORP | Tampa | Florida | 33615 | — |
| Clinical Site Partners, Inc. dba CSP Orlando | Winter Park | Florida | 32789 | — |
| Research by Design, LLC | Chicago | Illinois | 60643 | — |
| New Orleans Sinus Center (COVID-19 Testing) | Marrero | Louisiana | 70072 | — |
| Tandem Clinical Research GI, LLC | Marrero | Louisiana | 70072 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Excel Clinical research | Las Vegas | Nevada | 89109 | — |
| Meridian Clinical Research, LLC | Endwell | New York | 13760 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Accellacare | Wilmington | North Carolina | 28401 | — |
| Premier Medical Group | Clarksville | Tennessee | 37040 | — |
| PharmaTex Research, LLC | Amarillo | Texas | 79109 | — |
| ARC Clinical Research at William Cannon | Austin | Texas | 78745 | — |
| St Hope Foundation | Bellaire | Texas | 77401 | — |
| Conroe Willis Medical Research | Conroe | Texas | 77304 | — |
| South Texas Clinical Research | Corpus Christi | Texas | 78413 | — |
| SignatureCare Emergency Center | Houston | Texas | 77008 | — |
| Trio Clinical Trials, LLC | Houston | Texas | 77008 | — |
| C & R Research Services USA | Houston | Texas | 77022 | — |
| Next Level Urgent Care | Houston | Texas | 77057 | — |
| SMS Clinical Research, LLC | Mesquite | Texas | 75149 | — |
| SMS Clinical Research | Mesquite | Texas | 75149 | — |
| LinQ Research, LLC | Pearland | Texas | 77584 | — |
| Epic Medical Research | Red Oak | Texas | 75154 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| BFHC Research | San Antonio | Texas | 78249 | — |
| Tranquility Research | Webster | Texas | 77598 | — |
| TPMG (Tidewater Physicians Multispecialty Group) Clinical Research | Newport News | Virginia | 23606 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 128 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04960202, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 9, 2025 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04960202 live on ClinicalTrials.gov.