ClinicalTrials.gov record
A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)
ClinicalTrials.gov ID: NCT04964089
Public ClinicalTrials.gov record NCT04964089. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Randomized, Double-masked, Active Comparator-controlled, Multi-center, Two-arm, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)
Study identification
- NCT ID
- NCT04964089
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Kodiak Sciences Inc
- Industry
- Enrollment
- 557 participants
Conditions and interventions
Conditions
Interventions
- Aflibercept Drug
- KSI-301 Drug
- Sham Procedure Other
Drug · Other
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 22, 2021
- Primary completion
- Mar 27, 2023
- Completion
- Apr 5, 2023
- Last update posted
- Jul 2, 2024
2021 – 2023
United States locations
- U.S. sites
- 65
- U.S. states
- 28
- U.S. cities
- 63
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Research Institute, LLC | Phoenix | Arizona | 85014 | — |
| Northwest Arkansas Retina Associates | Springdale | Arkansas | 72762 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Eye Medical Center of Fresno | Fresno | California | 93720 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| UCSD Jacobs Retina Center | La Jolla | California | 92037 | — |
| Retina Associates of Orange County | Laguna Hills | California | 92653 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| Retina Consultants of San Diego | Poway | California | 92064 | — |
| Retina Consultants of Southern California | Redlands | California | 92374 | — |
| Retinal Consultants Medical Group Inc | Sacramento | California | 95819 | — |
| Orange County Retina Medical Group | Santa Ana | California | 92705 | — |
| Colorado Retina Associates PC | Lakewood | Colorado | 80228 | — |
| Retina Group of New England | Waterford | Connecticut | 06385 | — |
| Florida Eye Microsurgical Institute | Boynton Beach | Florida | 33426 | — |
| Rand Eye Institute | Deerfield Beach | Florida | 33064 | — |
| Retina Health Center | Fort Myers | Florida | 33907 | — |
| National Ophthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33703 | — |
| Retina Associates of Florida | Tampa | Florida | 33609 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Springfield Clinic LLP | Springfield | Illinois | 62703 | — |
| Talley Eye | Evansville | Indiana | 47710 | — |
| Wolfe Eye Clinic | West Des Moines | Iowa | 50266 | — |
| Retina Associates PA | Lenexa | Kansas | 66215 | — |
| Retina Associates of Kentucky | Lexington | Kentucky | 40509 | — |
| Retina Group of Washington | Chevy Chase | Maryland | 20815 | — |
| Cumberland Valley Retina Consultants PC | Hagerstown | Maryland | 21740 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| New England Retina Consultants | Springfield | Massachusetts | 01103 | — |
| Vitreo Retinal Associates PC | Worcester | Massachusetts | 01603 | — |
| Foundation for Vision Research | Grand Rapids | Michigan | 49525 | — |
| Associated Retinal Consultants PC | Royal Oak | Michigan | 78073 | — |
| Vitreoretinal Surgery PA | Edina | Minnesota | 55435 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| The Retina Center of New Jersey | Bloomfield | New Jersey | 07017 | — |
| NJ Retina | Teaneck | New Jersey | 07605 | — |
| Retina-Vitreous Surgeons of Central NY | Liverpool | New York | 13088 | — |
| Retina Associates of Western NY | Rochester | New York | 14620 | — |
| Western Carolina Retinal Associate PA | Asheville | North Carolina | 28803 | — |
| Retina Associates of Cleveland | Cleveland | Ohio | 44130 | — |
| Cleveland Clinic Foundation, Cole Eye Institute | Cleveland | Ohio | 44195 | — |
| Retina Northwest | Portland | Oregon | 97210 | — |
| Retina Consultants, LLC | Salem | Oregon | 97302 | — |
| Cascade Medical Research Institute | Springfield | Oregon | 97477 | — |
| MidAtlantic Retina | Philadelphia | Pennsylvania | 19107 | — |
| Retina Research of Beaufort | Beaufort | South Carolina | 29902 | — |
| Charleston Neuroscience Institute | Ladson | South Carolina | 29456 | — |
| Palmetto Retina Center | West Columbia | South Carolina | 296169 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Southeastern Retina Associates PC | Knoxville | Tennessee | 37909 | — |
| Tennessee Retina PC | Nashville | Tennessee | 37203 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Retina Consultants of Texas | Houston | Texas | 77030 | — |
| Retina Consultants of Texas-(Katy) | Katy | Texas | 77494 | — |
| Texas Retina Associates | Plano | Texas | 75075 | — |
| Austin Retina Associates (Round Rock) | Round Rock | Texas | 78681 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas - (Woodlands) | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| Spokane Eye | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04964089, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 2, 2024 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04964089 live on ClinicalTrials.gov.