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Completed Phase 2 Interventional Results available

A Study to Assess the Safety, Efficacy and Tolerability of AZD8233 Treatment in Participants With Hyperlipidaemia

ClinicalTrials.gov ID: NCT04964557

Public ClinicalTrials.gov record NCT04964557. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 22, 2026, 5:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomised, Parallel, Double-Blind, Placebo-Controlled Phase 2b Study to Assess the Safety, Tolerability and Efficacy of AZD8233 Treatment in Participants With Hyperlipidaemia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

AZD8233 is a PCSK9-targeted ASO for the reduction of circulating levels of LDL-C. This study aims to evaluate safety, efficacy and tolerability of AZD8233.

Study identification

NCT ID
NCT04964557
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
411 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 6, 2021
Primary completion
Jul 14, 2022
Completion
Jul 14, 2022
Last update posted
Dec 14, 2023

2021 – 2022

United States locations

U.S. sites
16
U.S. states
11
U.S. cities
15
Facility City State ZIP Site status
Research Site Huntsville Alabama 35801
Research Site Canoga Park California 91303
Research Site Lincoln California 95648
Research Site Inverness Florida 34452
Research Site Jacksonville Florida 32216
Research Site Pembroke Pines Florida 33024
Research Site Meridian Idaho 83646
Research Site Indianapolis Indiana 46260
Research Site New Windsor New York 12553
Research Site Greensboro North Carolina 27408
Research Site Fargo North Dakota 58104
Research Site Cincinnati Ohio 45219
Research Site Cincinnati Ohio 45246
Research Site Stow Ohio 44224
Research Site Mt. Pleasant South Carolina 29464
Research Site Suffolk Virginia 23435

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04964557, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 14, 2023 · Synced Sep 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04964557 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →