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Completed Phase 2 Interventional

A Study of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS)

ClinicalTrials.gov ID: NCT04968912

Public ClinicalTrials.gov record NCT04968912. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 3:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Placebo-controlled, Double-blind, Multicenter Study to Assess the Efficacy and Safety of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy and safety of nipocalimab in participants with primary Sjogren's syndrome (pSS) versus placebo.

Study identification

NCT ID
NCT04968912
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
163 participants

Conditions and interventions

Interventions

Other · Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 20, 2021
Primary completion
Oct 22, 2023
Completion
Nov 29, 2023
Last update posted
Nov 4, 2025

2021 – 2023

United States locations

U.S. sites
25
U.S. states
15
U.S. cities
24
Facility City State ZIP Site status
Anniston Medical Clinic Anniston Alabama 36207
Arizona Arthritis and Rheumatology Research PLLC Glendale Arizona 85306
Arizona Arthritis & Rheumatology Research, PLLC Mesa Arizona 85210
St. Jude Heritage Medical Group Fullerton California 92835
Inland Rheumatology Clinical Trials, Inc. Upland California 91786
Colorado Arthritis Associates Denver Colorado 80228
Denver Arthritis Clinic Denver Colorado 80230
Rheumatology Associates Of South Florida Boca Raton Florida 33486
Bay Area Arthritis and Osteoporosis Brandon Florida 33511
Centre for Rheumatology, Immunology and Arthritis Fort Lauderdale Florida 33309
University of Florida Health Jacksonville Jacksonville Florida 32209
Omega Research Consultants Orlando Florida 32835
Clinical Investigation Specialists Gurnee Illinois 60031
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
University of Kansas Medical Center Kansas City Kansas 66160
St. Paul Rheumatology P A Eagan Minnesota 55121
North Mississippi Medical Clinics Tupelo Mississippi 38801
PMG Research of Salisbury Salisbury North Carolina 28144
Altoona Center For Clinical Research Duncansville Pennsylvania 16635
University of Pennsylvania Philadelphia Pennsylvania 19104
Columbia Arthritis Center Columbia South Carolina 29204
West Tennessee Research Institute Jackson Tennessee 38305
Dr. Ramesh Gupta Memphis Tennessee 38119
Austin Regional Clinic Austin Texas 78731-3146
Trinity Clinical Research, LLC Carrollton Texas 75007

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 44 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04968912, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 4, 2025 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04968912 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →