A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy
Public ClinicalTrials.gov record NCT04977336. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-blind, Placebo-controlled, Dose-ranging, Study Evaluating the Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of VX-548 doses in treating acute pain after a bunionectomy.
Study identification
- NCT ID
- NCT04977336
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 274 participants
Conditions and interventions
Conditions
Interventions
- VX-548 Drug
- HB/APAP Drug
- Placebo (matched to VX-548) Drug
- Placebo (matched to HB/APAP) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 19, 2021 (Actual)
- Primary completion
- Feb 17, 2022 (Actual)
- Completion
- Mar 4, 2022 (Actual)
- Last update posted
- Jun 25, 2025
2021 – 2022
United States locations
- U.S. sites
- 12
- U.S. states
- 8
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Shoals Medical Trials Inc. | Sheffield | Alabama | 35660 | — |
| Arizona Research Center | Phoenix | Arizona | 85053 | — |
| Anaheim Clinical Trials | Anaheim | California | 92801 | — |
| Lotus Clinical Research | Pasadena | California | 91105 | — |
| New Hope Research Development | Tarzana | California | 91356 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Chesapeake Research Group | Pasadena | Maryland | 21122 | — |
| Midwest Clinical Research Center | Dayton | Ohio | 45417 | — |
| First Surgical Hospital | Bellaire | Texas | 77401 | — |
| Legent Orthopedic Hospital | Carrollton | Texas | 75006 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78229 | — |
| JBR Clinical Research | Salt Lake City | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04977336, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 25, 2025 · Synced Oct 16, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04977336 live on ClinicalTrials.gov.