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Completed Phase 1 Interventional Results available

Study of ALXN1850 in Participants With Hypophosphatasia (HPP)

ClinicalTrials.gov ID: NCT04980248

Public ClinicalTrials.gov record NCT04980248. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 6:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Open-label, Dose-escalating Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ALXN1850 in Adults With Hypophosphatasia

Study identification

NCT ID
NCT04980248
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Alexion Pharmaceuticals, Inc.
Industry
Enrollment
15 participants

Conditions and interventions

Interventions

  • ALXN1850 Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 64 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 27, 2021
Primary completion
Aug 23, 2022
Completion
Aug 23, 2022
Last update posted
Dec 26, 2024

2021 – 2022

United States locations

U.S. sites
4
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
Research Site Las Vegas Nevada 89113
Research Site Columbus Ohio 43203
Research Site Nashville Tennessee 37232
Research Site Austin Texas 78744

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04980248, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 26, 2024 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04980248 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →