ClinicalTrials.gov record
ACTIV-5 / Big Effect Trial (BET-C) for the Treatment of COVID-19
ClinicalTrials.gov ID: NCT04988035
Public ClinicalTrials.gov record NCT04988035. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter Platform Trial of Putative Therapeutics for the Treatment of COVID-19 in Hospitalized Adults
Study identification
- NCT ID
- NCT04988035
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 201 participants
Conditions and interventions
Conditions
Interventions
- Danicopan Drug
- Placebo Other
- Remdesivir Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2, 2021
- Primary completion
- Apr 22, 2022
- Completion
- Apr 22, 2022
- Last update posted
- Jun 7, 2023
2021 – 2022
United States locations
- U.S. sites
- 39
- U.S. states
- 19
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham School of Medicine - Infectious Disease | Birmingham | Alabama | 35233 | — |
| Kern Medical Center | Bakersfield | California | 93306-4018 | — |
| UCSF Fresno Center for Medical Education and Research - Clinical Research Center | Fresno | California | 93721 | — |
| University of California Los Angeles Medical Center - Westwood Clinic | Los Angeles | California | 90095 | — |
| Hoag Hospital Newport Beach | Newport Beach | California | 92663 | — |
| Penrose Hospital - Emergency Medicine | Colorado Springs | Colorado | 80907 | — |
| St. Francis Medical Center | Colorado Springs | Colorado | 80923 | — |
| St. Anthony Hospital | Lakewood | Colorado | 80228-1704 | — |
| St. Anthony Hospital North Health Campus | Westminster | Colorado | 80023 | — |
| Nuvance Health Danbury Hospital - Infectious Disease | Danbury | Connecticut | 06810 | — |
| Yale School of Medicine - The Anlyan Center for Medical Research & Education - Immunobiology | New Haven | Connecticut | 06519-1612 | — |
| Nuvance Health - Norwalk Hospital - Asthma Pulmonary and Critical Care Medicine | Norwalk | Connecticut | 06856 | — |
| University of Florida Health - Shands Hospital - Division of Infectious Diseases and Global Medicine | Gainesville | Florida | 32610 | — |
| Mayo Clinic Florida | Jacksonville | Florida | 32224 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Carle Foundation Hospital | Urbana | Illinois | 61801 | — |
| Northwestern Medicine - Central DuPage Hospital - Infectious Disease | Winfield | Illinois | 60190 | — |
| Norton Healthcare | Louisville | Kentucky | 40202 | — |
| University of Louisville - Division of Infectious Diseases | Louisville | Kentucky | 40202 | — |
| Brigham and Women's Hospital - Infectious Diseases | Boston | Massachusetts | 02115-6110 | — |
| William Beaumont Hospital - Royal Oak Campus - Infectious Disease | Royal Oak | Michigan | 48073 | — |
| Hennepin Healthcare Research Institute | Minneapolis | Minnesota | 55415 | — |
| Mayo Clinic, Rochester - Infectious Diseases | Rochester | Minnesota | 55905-0001 | — |
| University of Nebraska Medical Center - Infectious Diseases | Omaha | Nebraska | 68105 | — |
| The State University of New York - University at Buffalo - Department of Medicine | Buffalo | New York | 14203 | — |
| Mount Sinai School of Medicine - Medicine - Infectious Diseases | New York | New York | 10029-6504 | — |
| Nuvance Health - Vassar Brothers Medical Center | Poughkeepsie | New York | 12601 | — |
| Stony Brook Medicine - Stony Brook University Hospita | Stony Brook | New York | 11794 | — |
| Jacobi Medical Center | The Bronx | New York | 10461-1119 | — |
| Montefiore Medical Center - Infectious Diseases | The Bronx | New York | 10467-2401 | — |
| Wake Forest Baptist Health - Infectious Diseases | Winston-Salem | North Carolina | 27157 | — |
| St. Charles Health System - St. Charles Bend Hospital | Bend | Oregon | 97701 | — |
| Doylestown Hospital | Doylestown | Pennsylvania | 18901 | — |
| Penn State Health Milton S. Hershey Medical Center - Division of Infectious Diseases | Hershey | Pennsylvania | 17033 | — |
| Kent County Memorial Hospital | Warwick | Rhode Island | 02886 | — |
| Hendrick Health - Hendrick Medical Center | Abilene | Texas | 79601 | — |
| Baylor Scott & White Health - Baylor University Medical Center - North Texas Infectious Disease Consultants | Dallas | Texas | 75246 | — |
| University of Utah - Infectious Diseases | Salt Lake City | Utah | 84132 | — |
| West Virginia University - Infectious Diseases Clinic | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04988035, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 7, 2023 · Synced Jul 23, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04988035 live on ClinicalTrials.gov.