Open-Label Safety Study of Acoramidis (AG10) in Symptomatic ATTR Participants
Public ClinicalTrials.gov record NCT04988386. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label Extension and Safety Monitoring Study of Acoramidis (AG10) in Participants With Symptomatic Transthyretin Amyloid Cardiomyopathy Who Completed the Phase 3 ATTRibute-CM Trial (AG10-301)
Study identification
- NCT ID
- NCT04988386
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eidos Therapeutics, a BridgeBio company
- Industry
- Enrollment
- 389 participants
Conditions and interventions
Interventions
- Acoramidis (AG10) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 26, 2021
- Primary completion
- Apr 14, 2028
- Completion
- May 14, 2028
- Last update posted
- Oct 13, 2025
2021 – 2028
United States locations
- U.S. sites
- 26
- U.S. states
- 17
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of Colorado Hospital - Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| NorthShore University Health System | Evanston | Illinois | 60201 | — |
| MedStar Medical Group Cardiology at Franklin Square | Baltimore | Maryland | 21237 | — |
| Boston University Medical Center General Clinical Research Unit | Boston | Massachusetts | 02118 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| New York University Langone Health | New York | New York | 10016 | — |
| Columbia University Irving Medical Center | New York | New York | 10032 | — |
| Laurelton Heart Specialists | Rosedale | New York | 11422 | — |
| Montefiore Medical Center at Hutchinson | The Bronx | New York | 10461 | — |
| Duke University Health System - Duke Clinic | Durham | North Carolina | 27710 | — |
| Cleveland Clinic Main Campus | Cleveland | Ohio | 44195 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center (UPMC) | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Virginia Commonwealth University Health System | Richmond | Virginia | 23219 | — |
| Roanoke Heart Institute | Roanoke | Virginia | 24014 | — |
| University of Washington School of Medicine | Seattle | Washington | 98195 | — |
| Providence Sacred Heart Children's Hospital | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04988386, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 13, 2025 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04988386 live on ClinicalTrials.gov.