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Completed Phase 4 Interventional Results available

EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients

ClinicalTrials.gov ID: NCT04998604

Public ClinicalTrials.gov record NCT04998604. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:47 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Head-to-head Comparison of Dupilumab Versus Omalizumab in Severe Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) and Comorbid Asthma Patients

Study identification

NCT ID
NCT04998604
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Sanofi
Industry
Enrollment
360 participants

Conditions and interventions

Interventions

  • Dupilumab Drug
  • Omalizumab Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 26, 2021
Primary completion
Oct 15, 2024
Completion
Dec 26, 2024
Last update posted
Oct 22, 2025

2021 – 2024

United States locations

U.S. sites
16
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
Cedars Sinai Medical Center Site Number : 8400026 Los Angeles California 90048
Asthma Allergy & Immunology Clinical Research Unit Site Number : 8400027 Tampa Florida 33613
Northwestern University Site Number : 8400001 Chicago Illinois 60611
University of Illinois Chicago Illinois 60612
Advanced ENT and Allergy Site Number : 8400013 Louisville Kentucky 40220
University of Missouri Health Care - University Hospital Site Number : 8400016 Columbia Missouri 65212
Northwell Health Site Number : 8400044 Great Neck New York 11021
University of Rochester Site Number : 8400015 Rochester New York 14642
Cleveland Clinic Foundation Site Number : 8400029 Cleveland Ohio 44195
Optimed Research, LTD Site Number : 8400014 Columbus Ohio 43235
Allergy, Asthma and Clinical Research Center Site Number : 8400037 Oklahoma City Oklahoma 73120
Essential Medical Research, LLC Site Number : 8400024 Tulsa Oklahoma 74137
Oregon Health & Science University Site Number : 8400031 Portland Oregon 97239
University of Texas Health Science Center- Site Number : 8400019 Houston Texas 77030
Chryaslis Clinical Research Site Number : 8400017 St. George Utah 84790
Eastern Virginia Medical School Site Number : 8400010 Norfolk Virginia 23507

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 71 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04998604, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 22, 2025 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04998604 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →