Trial on the Safety and Efficacy of MLS-101 in Patients With Uncontrolled Hypertension
Public ClinicalTrials.gov record NCT05001945. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Dose-ranging, Multicenter Phase 2 Study to Evaluate the Safety, Efficacy, and Tolerability of MLS-101 in Subjects With Uncontrolled Hypertension
Study identification
- NCT ID
- NCT05001945
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Mineralys Therapeutics Inc.
- Industry
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- MLS-101 (Part I) Drug
- Placebo (Part I) Other
- Placebo (Part II) Other
- MLS-101 (Part II) Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2021
- Primary completion
- Sep 6, 2022
- Completion
- Oct 6, 2022
- Last update posted
- Jan 4, 2024
2021 – 2022
United States locations
- U.S. sites
- 44
- U.S. states
- 14
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site 103 | Lincoln | California | 95648 | — |
| Site 129 | Torrance | California | 90502 | — |
| Site 135 | Tustin | California | 92780 | — |
| Site 131 | Clearwater | Florida | 33765 | — |
| Site 105 | Coral Gables | Florida | 33134 | — |
| Site 108 | Greenacres City | Florida | 33467 | — |
| Site 134 | Jupiter | Florida | 33458 | — |
| Site 146 | Miami | Florida | 33126 | — |
| Site 137 | Miami | Florida | 33135 | — |
| Site 139 | Miami | Florida | 33135 | — |
| Site 143 | Miami | Florida | 33144 | — |
| Site 122 | Pembroke Pines | Florida | 33026 | — |
| Site 102 | Tampa | Florida | 91303 | — |
| Site 118 | Albany | Georgia | 31707 | — |
| Site 109 | Fayetteville | Georgia | 30214 | — |
| Site 125 | Lawrenceville | Georgia | 30044 | — |
| Site 136 | Arlington Heights | Illinois | 60005 | — |
| Site 138 | Bossier City | Louisiana | 71111 | — |
| Site 154 | Hammond | Louisiana | 70403 | — |
| Site 148 | Shreveport | Louisiana | 71105 | — |
| Site 114 | Slidell | Louisiana | 70458 | — |
| Site 116 | Jefferson City | Missouri | 65109 | — |
| Site 121 | St Louis | Missouri | 63141 | — |
| Site 123 | Las Vegas | Nevada | 89121 | — |
| Site 141 | Jamaica | New York | 11432 | — |
| Site 133 | Asheboro | North Carolina | 27203 | — |
| Site 113 | Charlotte | North Carolina | 28210 | — |
| Site 130 | Fayetteville | North Carolina | 28304 | — |
| Site 140 | Greensboro | North Carolina | 27408 | — |
| Site 104 | Morgantown | North Carolina | 28655 | — |
| Site 150 | Raleigh | North Carolina | 27612 | — |
| Site 153 | Cleveland | Ohio | 44195 | — |
| Site 115 | Rapid City | South Dakota | 57702 | — |
| Site 107 | Chattanooga | Tennessee | 37421 | — |
| Site 120 | Kingsport | Tennessee | 37660 | — |
| Site 152 | Nashville | Tennessee | 37232 | — |
| Site 151 | Arlington | Texas | 76012 | — |
| Site 145 | Cypress | Texas | 77429 | — |
| Site 132 | Dallas | Texas | 75224 | — |
| Site 124 | McKinney | Texas | 75071 | — |
| Site 147 | Mesquite | Texas | 75149 | — |
| Site 126 | Pearland | Texas | 77584 | — |
| Site 128 | Richland Hills | Texas | 76180 | — |
| Site 112 | Forest | Virginia | 24551 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05001945, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 4, 2024 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05001945 live on ClinicalTrials.gov.