Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

ClinicalTrials.gov ID: NCT05004129

Public ClinicalTrials.gov record NCT05004129. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:47 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of Tideglusib for the Treatment of Congenital or Childhood Onset DM1 (REACH CDM X)

Study identification

NCT ID: NCT05004129
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2, Phase 3
Lead sponsor: AMO Pharma Limited; Industry
Enrollment: 76 participants

Conditions and interventions

Conditions

Congenital Myotonic Dystrophy

Interventions

Tideglusib Drug

Drug

Eligibility (public fields only)

Age range: 6 Years to 45 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Aug 22, 2021
Primary completion: Dec 30, 2026
Completion: Dec 30, 2026
Last update posted: May 27, 2025

2021 – 2026

United States locations

U.S. sites: 10
U.S. states: 8
U.S. cities: 10

Facility	City	State	ZIP	Site status
Arkansas Children's Hospital	Little Rock	Arkansas	72202	Recruiting
University of California, Los Angeles (UCLA)	Los Angeles	California	90095	Enrolling by invitation
Stanford University	Palo Alto	California	94304	Enrolling by invitation
Lurie's Children's Hospital	Chicago	Illinois	60611	Recruiting
University of Iowa Hospitals and Clinics	Iowa City	Iowa	52242	Recruiting
University of Rochester - Medical Center	Rochester	New York	14642	Recruiting
University of Pittsburgh Medical Center	Pittsburgh	Pennsylvania	15213	Recruiting
University of Utah Clinical Neurosciences Center	Salt Lake City	Utah	84132	Recruiting
Children's Hospital of The King's Daughters	Norfolk	Virginia	23507	Withdrawn
Virginia Commonwealth University-Department of Neurology - Muscular Dystrophy Translational Research Program	Richmond	Virginia	23219	Completed

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05004129, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 27, 2025 · Synced Jul 21, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05004129 live on ClinicalTrials.gov.

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