Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participants
Public ClinicalTrials.gov record NCT05004181. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Trial to Evaluate the Safety and Immunogenicity of SARS-CoV-2 Monovalent and Multivalent RNA-based Vaccines in Healthy Subjects
Study identification
- NCT ID
- NCT05004181
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- BioNTech SE
- Industry
- Enrollment
- 1,380 participants
Conditions and interventions
Interventions
- BNT162b2 Biological
- Monovalent BNT162b2 (B.1.1.529.1) Biological
- Monovalent BNT162b2 (B.1.1.7) Biological
- Monovalent BNT162b2 (B.1.617.2) Biological
- Multivalent BNT162b2 (B.1.1.7 + B.1.617.2) Biological
- Observational Other
Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 24, 2021
- Primary completion
- Aug 15, 2023
- Completion
- Oct 3, 2023
- Last update posted
- Nov 21, 2024
2021 – 2023
United States locations
- U.S. sites
- 14
- U.S. states
- 8
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Collaborative Neuroscience Network LLC | Long Beach | California | 90806 | — |
| California Research Foundation | San Diego | California | 92123 | — |
| Clinical Research Consulting, Llc | Milford | Connecticut | 06460 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | — |
| Meridian Clinical Research | Savannah | Georgia | 31406 | — |
| Medpharmics, LLC | Gulfport | Mississippi | 39503 | — |
| Amici Clinical Research | Warren Township | New Jersey | 07059 | — |
| Rochester Clinical Research | Rochester | New York | 14609 | — |
| Aventiv Research Inc. | Columbus | Ohio | 43213 | — |
| ARC Clinical Research | Austin | Texas | 78745 | — |
| North Texas Infectious Diseases Consultants | Dallas | Texas | 75246 | — |
| Clinical Trials of Texas Inc. | San Antonio | Texas | 78229 | — |
| Diagnostics Research Group | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05004181, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 21, 2024 · Synced May 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05004181 live on ClinicalTrials.gov.