NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)
Public ClinicalTrials.gov record NCT05005845. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Vehicle-Controlled, Parallel Group Phase 2 Dose-Response Study to Determine Safety and Effectiveness of Two Concentrations of NFX-179 Gel in Subjects With Cutaneous Neurofibromas
Study identification
- NCT ID
- NCT05005845
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- NFlection Therapeutics, Inc.
- Industry
- Enrollment
- 199 participants
Conditions and interventions
Conditions
Interventions
- NFX-179 gel Drug
- Vehicle gel Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 28, 2021
- Primary completion
- Oct 1, 2023
- Completion
- Oct 1, 2023
- Last update posted
- Feb 16, 2026
2021 – 2023
United States locations
- U.S. sites
- 23
- U.S. states
- 18
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205-7199 | — |
| Northwest Arkansas Clinical Trials Center, PLLC | Rogers | Arkansas | 72758 | — |
| Center for Dermatology Clinical Research, Inc. | Fremont | California | 94538 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | — |
| University Clinical Trials, Inc. | San Diego | California | 92123 | — |
| Children's National Hospital | Washington D.C. | District of Columbia | 20010 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Northshore University HealthSystem | Evanston | Illinois | 60077 | — |
| Dawes Fretzin Clinical Research Group | Indianapolis | Indiana | 46250 | — |
| The Johns Hopkins School of Medicine | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Minnesota Clinical Study Center | New Brighton | Minnesota | 55112 | — |
| Skin Specialists, P.C. | Omaha | Nebraska | 68144 | — |
| Sadick Research Group, LLC | New York | New York | 10075 | — |
| Skin Search of Rochester, Inc. | Rochester | New York | 14623 | — |
| Wake Forest School of Medicine | Winston-Salem | North Carolina | 27157 | — |
| Apex Clinical Research Center, LLC | Mayfield Heights | Ohio | 44124 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Derm Dox Center for Dermatology | Sugarloaf | Pennsylvania | 18249 | — |
| Dermatology Treatment and Research Center | Dallas | Texas | 75230 | — |
| UTHealth McGovern Medical School | Houston | Texas | 77030 | — |
| University of Utah | Salt Lake City | Utah | 84108 | — |
| The Education & Research Foundation, Inc. | Lynchburg | Virginia | 24501 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05005845, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 16, 2026 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05005845 live on ClinicalTrials.gov.