Extension Study of ABP-20001 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 for Migraine Prevention
Public ClinicalTrials.gov record NCT05016661. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Dose-Blinded, Phase 2 Extension Study of ABP-450 (prabotulinumtoxinA) Purified Neurotoxin Complex for the Prevention of Migraine Headache
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase 2 Extension trial will evaluate the efficacy and safety of ABP-450 for migraine prevention in adults who suffer from six or more migraine days per month. The study will enroll approximately 666 patients across approximately 65 sites in the United States, Canada and Australia from the Phase 2 trial. Study subjects will be divided evenly across a low dose group and a high dose group. All patients will receive four treatment cycles of ABP-450 utilizing the Company's novel injection paradigm.
Study identification
- NCT ID
- NCT05016661
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 466 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 19, 2021 (Actual)
- Primary completion
- Jul 31, 2024 (Actual)
- Completion
- Aug 30, 2024 (Actual)
- Last update posted
- Sep 20, 2024
2021 – 2024
United States locations
- U.S. sites
- 48
- U.S. states
- 23
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MDFirst Research | Chandler | Arizona | 85226 | — |
| Elite Clinical Studies, LLC | Phoenix | Arizona | 85018 | — |
| Arizona Neuroscience Research | Phoenix | Arizona | 85032 | — |
| Clinical Research Consortium Arizona | Tempe | Arizona | 85281 | — |
| Axiom Research LLC | Colton | California | 92324 | — |
| Velocity Research San Diego | La Mesa | California | 91942 | — |
| Los Angeles Headache Center | Los Angeles | California | 90067 | — |
| Anderson Clinical Research | Redlands | California | 92374 | — |
| Artemis Institute For Clinical Research LLC - San Diego - ClinEdge - PPDS | San Diego | California | 92103 | — |
| Delta Waves LLC - Hunt - PPDS | Colorado Springs | Colorado | 80918 | — |
| Paradigm Clinical Research Centers | Wheat Ridge | Colorado | 80033 | — |
| New England Institute for Neurology and Headache | Stamford | Connecticut | 06905 | — |
| Quality Research of South Florida | Hialeah | Florida | 33016 | — |
| Sandhill Research, LLC | Lake Mary | Florida | 32746 | — |
| Canvas Clinical Research | Lake Worth | Florida | 33467 | — |
| BioMed Research Institute, INC | Miami | Florida | 33126 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Innovation Medical Research Center | Palmetto Bay | Florida | 33157 | — |
| Clinical Research of Central Florida - ClinEdge - PPDS | Winter Haven | Florida | 33810 | — |
| NeuroTrials Research Inc. - Clinedge - PPDS | Atlanta | Georgia | 30328 | — |
| Drug Studies America, Inc | Marietta | Georgia | 30060 | — |
| Velocity Clinical Research - Boise - ERN - PPDS | Meridian | Idaho | 83642 | — |
| Cedar Crosse Research Center | Chicago | Illinois | 60607 | — |
| Kansas Institute of Research, LLC | Overland Park | Kansas | 66211 | — |
| Crescent City Headache and Neurology Center | Chalmette | Louisiana | 70043 | — |
| Legacy Clinical Solutions: Tandem Clinical Research, LLC - Clinedge - PPDS | Marrero | Louisiana | 70072 | — |
| Boston Clinical Trials Inc | Boston | Massachusetts | 02131 | — |
| MedVadis Research | Waltham | Massachusetts | 02451 | — |
| Quest Research Institute - Hunt - PPDS | Farmington Hills | Michigan | 40825 | — |
| StudyMetrix Research, LLC | City of Saint Peters | Missouri | 63303 | — |
| Clinvest Research LLC | Springfield | Missouri | 65810 | — |
| Barrett Clinic, P.C. - Clinedge - PPDS | La Vista | Nebraska | 68128 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| Wake Research - CRCN, LLC | Las Vegas | Nevada | 89104 | — |
| Albuquerque Clinical Trials Inc - Clinedge - PPDS | Albuquerque | New Mexico | 87102 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Upstate Clinical Research Associates LLC | Williamsville | New York | 14221 | — |
| META Medical Research Institute, LLC | Dayton | Ohio | 45432 | — |
| Centricity Research Dublin Multispecialty | Dublin | Ohio | 43016 | — |
| The Orthopedic Foundation | New Albany | Ohio | 43054 | — |
| Thomas Jefferson University, Jefferson Headache Center | Philadelphia | Pennsylvania | 19107 | — |
| Preferred Primary Care Physicians | Pittsburgh | Pennsylvania | 15236 | — |
| WR-ClinSearch | Chattanooga | Tennessee | 37421 | — |
| Bryant Research Group | Nashville | Tennessee | 37203 | — |
| Alina Clinical Trials | Dallas | Texas | 75225 | — |
| Houston Neurology Associates | Sugar Land | Texas | 77478 | — |
| Aspen Clinical Research LLC - Clinedge - PPDS | Orem | Utah | 84058 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05016661, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 20, 2024 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05016661 live on ClinicalTrials.gov.