ClinicalTrials.gov record
Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH)
ClinicalTrials.gov ID: NCT05016882
Public ClinicalTrials.gov record NCT05016882. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety Investigation of NNC0194-0499 Co-administered With Semaglutide in Subjects With Non-alcoholic Steatohepatitis: a Dose-ranging, Placebo Controlled Trial
Study identification
- NCT ID
- NCT05016882
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Enrollment
- 698 participants
Conditions and interventions
Conditions
Interventions
- NNC0194 0499 50 mg/mL Drug
- Placebo (NNC0194-0499) Drug
- Semaglutide 3 mg/mL Drug
- Semaglutide placebo Drug
- NNC0174 0833 10 mg/mL Drug
- NNC0174 0833 placebo Drug
Drug
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 30, 2021
- Primary completion
- Dec 16, 2024
- Completion
- Mar 13, 2025
- Last update posted
- Nov 18, 2025
2021 – 2025
United States locations
- U.S. sites
- 70
- U.S. states
- 23
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North AL Health Res, LLC | Huntsville | Alabama | 35801 | — |
| The Institute for Liver Health | Chandler | Arizona | 85224 | — |
| Inst-Liver Hlth dba AZ Liver H | Peoria | Arizona | 85381 | — |
| Del Sol Research Management, LLC | Tucson | Arizona | 85715 | — |
| Hope Clinical Research | Canoga Park | California | 91303 | — |
| UCSD NAFLD Research Center | La Jolla | California | 92037 | — |
| OM Research LLC | Lancaster | California | 93534 | — |
| Digestive Hlth Res of SoCa | Long Beach | California | 90808 | — |
| Stanford Medicine | Redwood City | California | 94063 | — |
| UC Davis Hlth -Midtwn Ambu Cen | Sacramento | California | 95817 | — |
| Peak Gastro Assoc-Col Springs | Colorado Springs | Colorado | 80907 | — |
| Hartford Hsptl_Hartford | Hartford | Connecticut | 06106 | — |
| Integrity Clinical Research, LLC | Doral | Florida | 33122 | — |
| Miguel Rebollar PA | Hialeah | Florida | 33012 | — |
| Nature Coast Clinical Research_Inverness | Inverness | Florida | 34452 | — |
| UF Hlth Jacksonville | Jacksonville | Florida | 32224 | — |
| Florida Research Institute, LLC | Lakewood Rch | Florida | 34211 | — |
| ClinCloud,LLC | Maitland | Florida | 32751 | — |
| Optimus U, Corp | Miami | Florida | 33135 | — |
| Univ of Miami/Schiff Ctr | Miami | Florida | 33136 | — |
| Covenant Metabolic Specialists LLC | University Park | Florida | 34201 | — |
| ClinCloud, LLC | Viera E. | Florida | 32940 | — |
| Florida Medical Clinic Orlando Health | Zephyrhills | Florida | 33542 | — |
| Florida Medical Clinic, LLC | Zephyrhills | Florida | 33542 | — |
| Piedmont Healthcare | Atlanta | Georgia | 30309 | — |
| Digestive Healthcare of Georgia | Atlanta | Georgia | 30327 | — |
| Gastroenterology Assoc_ CGA | Macon | Georgia | 31201 | — |
| Gastroint Spec of Georgia | Marietta | Georgia | 30060 | — |
| EBGS Clinical Research Center, LLC | Snellville | Georgia | 30078 | — |
| Grand Teton Gastroenterology | Idaho Falls | Idaho | 83404-7590 | — |
| Digestive Research Alliance of Michiana | South Bend | Indiana | 46635 | — |
| University Of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Kansas Medical Clinic, PA | Topeka | Kansas | 66606 | — |
| Tandem Clinical Research - Houma | Houma | Louisiana | 70363 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| Tandem Clinical Research - Metairie | Metairie | Louisiana | 70006 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Mercy Medical Center, GI Research | Baltimore | Maryland | 21202 | — |
| Walter Reed Nat Mil Md Ctr | Bethesda | Maryland | 20889 | — |
| Henry Ford Hospital_Detroit | Detroit | Michigan | 48202 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| Univ of Nebraska Medical CTR | Omaha | Nebraska | 68198-3020 | — |
| AIG Digestive Disease Research | Florham Park | New Jersey | 07932 | — |
| NYU Grossman School of Med | New York | New York | 10016 | — |
| Weill Cornell Med Coll-NYPH | New York | New York | 10065 | — |
| Univ Hosp Cleveland Med Ctr | Cleveland | Ohio | 44106 | — |
| Ohio State Univ Wexner Med Ctr | Columbus | Ohio | 43210 | — |
| DSI Research,LLC | Springboro | Ohio | 45066 | — |
| Geisinger Clinic | Danville | Pennsylvania | 17822-2111 | — |
| Pennsylvania State University | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107-5244 | — |
| UPMC Center for Liver Diseases | Pittsburgh | Pennsylvania | 15213 | — |
| UPMC_Center for Liver Care | Pittsburgh | Pennsylvania | 15213 | — |
| Digestive Health Res-TSMC | Hermitage | Tennessee | 37076 | — |
| Quality Medical Research | Nashville | Tennessee | 37211 | — |
| Texas Clin Res Inst, LLC | Arlington | Texas | 76012 | — |
| Liver Ins@ Mthdist DTX Med Cen | Dallas | Texas | 75203 | — |
| Centex Studies, Inc. | Houston | Texas | 77058 | — |
| Amir Ali Hassan, MD, PA | Houston | Texas | 77089 | — |
| Texas Diabetes &Endocrinology | Round Rock | Texas | 78681 | — |
| Amer. Rrsch Corp-TX Liver Inst | San Antonio | Texas | 78215 | — |
| Olympus Clinical Research | Sugar Land | Texas | 77478 | — |
| Impact Research | Waco | Texas | 76710 | — |
| Digestive Hlth Res of N Texas | Wichita Falls | Texas | 76301 | — |
| Inova Fairfax Medical Campus | Falls Church | Virginia | 22042 | — |
| Bon Secours Richmond Community Hospital LLC | Richmond | Virginia | 23226 | — |
| Gastroent Consult of SW VA | Roanoke | Virginia | 24014 | — |
| Swedish med ctr org trans-lvr ctr | Seattle | Washington | 98104 | — |
| Liver Institute NW | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 185 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05016882, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 18, 2025 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05016882 live on ClinicalTrials.gov.