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Active, not recruiting Phase 2 Interventional Results available

A Study of TAK-007 in Adults With Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

ClinicalTrials.gov ID: NCT05020015

Public ClinicalTrials.gov record NCT05020015. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 12:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Open-label, Multicenter Study of the Safety and Efficacy of TAK-007 in Adult Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study has 2 parts. The main aim of Part 1 is to check for side effects from TAK-007 in adults with relapsed or refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL), The main aim of Part 2 is to learn whether lymphoma disease responds to treatment with TAK-007 in adults with r/r B-cell NHL or iNHL. Participants will receive 3 days of chemotherapy to reduce a type of white blood cells called lymphocytes, in the blood. This is called lymphodepleting chemotherapy (LDC) or lymphodepletion. After LDC, patients will receive a single injection of TAK-007 or three weekly injections of TAK-007 (multi-dose injection). After this, participants will regularly visit the clinic for check-ups.

Study identification

NCT ID
NCT05020015
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Takeda
Industry
Enrollment
27 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 11, 2021
Primary completion
Jun 15, 2024
Completion
Dec 19, 2038
Last update posted
Mar 30, 2026

2021 – 2038

United States locations

U.S. sites
15
U.S. states
13
U.S. cities
15
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35249
Cedars Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute Los Angeles California 90048
MedStar Georgetown University Medical Center Washington D.C. District of Columbia 20007
Sylvester Comprehensive Cancer Center University of Miami Hospitals and Clinics Miami Florida 33136
Northside Hospital Atlanta Georgia 30342
Northwestern Memorial Hospital Chicago Illinois 60611
University of Michigan Comprehensive Cancer Center Ann Arbor Michigan 48109
Columbia University Medical Center New York New York 10032
Montefiore Medical Center The Bronx New York 10467
DUHS Duke Blood Cancer Center Durham North Carolina 27705
Oregon Health and Science University Portland Oregon 97239
Thomas Jefferson University Sidney Kimmer Cancer Center, Clinical Research Organization Philadelphia Pennsylvania 19107
Saint Davids South Austin Medical Center Austin Texas 78704
University of Texas MD Anderson Cancer Center Houston Texas 77030
University of Virginia Comprehensive Cancer Center Charlottesville Virginia 22903

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05020015, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 30, 2026 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05020015 live on ClinicalTrials.gov.

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