A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor
Public ClinicalTrials.gov record NCT05021991. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Clinical Trial to Evaluate the Efficacy, Tolerability, and Safety of PRAX-944 in the Treatment of Adults With Essential Tremor
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This multi-center, randomized, double-blinded, placebo-controlled, dose-range-finding clinical trial (with an optional Extension comprised of an Extension Double-blind (DB) Lead in Period followed by an Extension Open-label (OL) Period) that will assess the efficacy, safety, and tolerability of PRAX 944 in participants aged 18 years or older who have a diagnosis of Essential Tremor (ET) and have had symptoms for at least 3 years.
Study identification
- NCT ID
- NCT05021991
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 133 participants
Conditions and interventions
Conditions
Interventions
- 100 mg PRAX-944 Drug
- 60 mg PRAX-944 Drug
- Placebo Drug
- Flexibly dosed 20 mg to 100 mg PRAX-944 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 14, 2021 (Actual)
- Primary completion
- Feb 9, 2023 (Actual)
- Completion
- Feb 29, 2024 (Actual)
- Last update posted
- Mar 13, 2024
2021 – 2024
United States locations
- U.S. sites
- 35
- U.S. states
- 21
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Praxis Research Site | Birmingham | Alabama | 35294 | — |
| Praxis Research Site | Little Rock | Arkansas | 72205 | — |
| Praxis Research Site | San Diego | California | 92103 | — |
| Praxis Research Site | Santa Monica | California | 90404 | — |
| Praxis Research Site | Torrance | California | 90503 | — |
| Praxis Research Site | Aurora | Colorado | 80045 | — |
| Praxis Research Site | Boca Raton | Florida | 33486 | — |
| Praxis Research Site | Gainesville | Florida | 32608 | — |
| Praxis Research Site | Jacksonville | Florida | 32209 | — |
| Praxis Research Site | Port Charlotte | Florida | 33980 | — |
| Praxis Research Site | St. Petersburg | Florida | 33713 | — |
| Praxis Research Site | Tampa | Florida | 33612 | — |
| Praxis Research Site | West Palm Beach | Florida | 33407 | — |
| Praxis Research Site | Chicago | Illinois | 60612 | — |
| Praxis Research Site | Kansas City | Kansas | 66160 | — |
| Praxis Research Site | Louisville | Kentucky | 40202 | — |
| Praxis Research Site | Rockville | Maryland | 20852 | — |
| Praxis Research Site | Boston | Massachusetts | 02118 | — |
| Praxis Research Site | Burlington | Massachusetts | 01805 | — |
| Praxis Research Site | Farmington Hills | Michigan | 48334 | — |
| Praxis Research Site | Golden Valley | Minnesota | 55427 | — |
| Praxis Research Site | Las Vegas | Nevada | 89106 | — |
| Praxis Research Site | New York | New York | 10029 | — |
| Praxis Research Site | New York | New York | 10032 | — |
| Praxis Research Site | Cincinnati | Ohio | 45212 | — |
| Praxis Research Site | Philadelphia | Pennsylvania | 19107 | — |
| Praxis Research Site | Georgetown | Texas | 78628 | — |
| Praxis Research Site | Houston | Texas | 77030 | — |
| Praxis Research Site | Round Rock | Texas | 78681 | — |
| Praxis Research Site | Burlington | Vermont | 05401 | — |
| Praxis Research Site | Alexandria | Virginia | 22311 | — |
| Praxis Research Site | Virginia Beach | Virginia | 23456 | — |
| Praxis Research Site | Kirkland | Washington | 98034 | — |
| Praxis Research Site | Spokane | Washington | 99202 | — |
| Praxis Research Site | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05021991, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 13, 2024 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05021991 live on ClinicalTrials.gov.