NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies
Public ClinicalTrials.gov record NCT05023486. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Multicenter, open-label study in patients with advanced or metastatic solid tumor malignancies to evaluate the safety, tolerability, and preliminary anti-tumor efficacy, PK, and pharmacodynamics of continuously dosed NP-G2-044 monotherapy and NP-G2-044 in combination with anti-PD-1 therapy.
Study identification
- NCT ID
- NCT05023486
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 121 participants
Conditions and interventions
Interventions
- NP-G2-044 Monotherapy Drug
- Anti-PD-1 Therapy Drug
- NP-G2-044 Combination therapy Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 7, 2021 (Actual)
- Primary completion
- Jun 30, 2026 (Actual)
- Completion
- Jun 30, 2026 (Actual)
- Last update posted
- Oct 9, 2026
2021 – 2026
United States locations
- U.S. sites
- 18
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Honor Health Research Institute | Scottsdale | Arizona | 85258 | — |
| University of Arizona - Cancer Center | Tucson | Arizona | 85719 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| City of Hope | Duarte | California | 91010 | — |
| City of Hope Irvine Lennar | Irvine | California | 92618 | — |
| Hoag Memorial Hospital Presbyterian - Gynecologic Oncology Associates | Newport Beach | California | 92663 | — |
| Nuvance Health | Norwalk | Connecticut | 06856 | — |
| University of Florida (UF) - Shands Cancer Center | Gainesville | Florida | 32610 | — |
| Indiana University (IU) Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | — |
| University of Kansas Cancer Center | Fairway | Kansas | 66205 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Atlantic Health System - Morristown Medical Center | Morristown | New Jersey | 07962 | — |
| University of Cincinnati (UC) - Cancer Institute | Cincinnati | Ohio | 45219 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| University of Texas Southwestern | Dallas | Texas | 75390 | — |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | — |
| Virginia Commonwealth University - Massey Cancer Center | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05023486, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 9, 2026 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05023486 live on ClinicalTrials.gov.