Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab
Public ClinicalTrials.gov record NCT05029882. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 First in Human Study Evaluating Safety, Pharmacokinetics and Efficacy of ABBV-400 as Monotherapy and in Combination With Bevacizumab in Adult Subjects With Advanced Solid Tumors
Study identification
- NCT ID
- NCT05029882
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 520 participants
Conditions and interventions
Conditions
Interventions
- ABBV-400 Drug
- Trifluridine/Tipiracil Drug
- Bevacizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 12, 2021
- Primary completion
- Oct 31, 2027
- Completion
- Oct 31, 2027
- Last update posted
- Oct 28, 2025
2021 – 2027
United States locations
- U.S. sites
- 18
- U.S. states
- 13
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California, Los Angeles /ID# 243841 | Los Angeles | California | 90095 | — |
| University Of Colorado Denver /ID# 231574 | Aurora | Colorado | 80045-2530 | — |
| Yale School of Medicine /ID# 248418 | New Haven | Connecticut | 06519 | — |
| University of Illinois Hospital and Health Sciences System /ID# 251386 | Chicago | Illinois | 60607 | — |
| Fort Wayne Medical Oncology and Hematology - Fort Wayne - East Dupont Road /ID# 267338 | Fort Wayne | Indiana | 46825 | — |
| Indiana University Melvin and Bren Simon Cancer Center /ID# 245133 | Indianapolis | Indiana | 46202-5112 | — |
| Community Health Network, Inc. /ID# 245331 | Indianapolis | Indiana | 46250-2042 | — |
| Comprehensive Cancer Centers of Nevada /ID# 242930 | Henderson | Louisiana | 89052 | — |
| START Midwest /ID# 231551 | Grand Rapids | Michigan | 49546-7062 | — |
| Memorial Sloan Kettering Cancer Center-Koch Center /ID# 250668 | New York | New York | 10065-6007 | — |
| Duke Cancer Institute /ID# 247236 | Durham | North Carolina | 27710 | — |
| Carolina BioOncology Institute /ID# 231541 | Huntersville | North Carolina | 28078 | — |
| Duplicate_Gabrail Cancer Center Research /ID# 248419 | Canton | Ohio | 44718 | — |
| MD Anderson Cancer Center at Texas Medical Center /ID# 248656 | Houston | Texas | 77030-4000 | — |
| Oncology Consultants /ID# 267347 | Houston | Texas | 77030 | — |
| NEXT Oncology /ID# 231578 | San Antonio | Texas | 78229 | — |
| Virginia Cancer Specialists - Fairfax /ID# 231575 | Fairfax | Virginia | 22031 | — |
| Northwest Medical Specialties Tacoma /ID# 267339 | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 64 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05029882, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 28, 2025 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05029882 live on ClinicalTrials.gov.