ClinicalTrials.gov record
Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease
ClinicalTrials.gov ID: NCT05030428
Public ClinicalTrials.gov record NCT05030428. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Multicenter Trial, Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Participants With Established Cardiovascular Disease (VICTORION-2 PREVENT)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Study CKJX839B12302 is a pivotal Phase III trial to evaluate the benefits of inclisiran on major adverse cardiovascular (MACE) events in participants with established cardiovascular disease (CVD).
Study identification
- NCT ID
- NCT05030428
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 17,004 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 23, 2021 (Actual)
- Primary completion
- May 10, 2027 (Estimated)
- Completion
- May 10, 2027 (Estimated)
- Last update posted
- Aug 25, 2026
2021 – 2027
United States locations
- U.S. sites
- 271
- U.S. states
- 43
- U.S. cities
- 217
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB St Vincents | Birmingham | Alabama | 35211 | — |
| Eastern Shore Research Institute | Fairhope | Alabama | 36532 | — |
| G and L Research LLC | Foley | Alabama | 36535 | — |
| Alaska Heart and Vascular | Anchorage | Alaska | 99508 | — |
| Mercy Gilbert Medical Center | Gilbert | Arizona | 85297 | — |
| Cardiovascular Associates of Mesa | Mesa | Arizona | 85206 | — |
| Elite Clinical Studies | Phoenix | Arizona | 85018 | — |
| HonorHealth Heart Group Deer Valley | Scottsdale | Arizona | 85258 | — |
| Clinical Research Inst of Arizona | Sun City West | Arizona | 85375 | — |
| Pima Heart And Vascular Clin Rch | Tucson | Arizona | 85741 | — |
| ARcare Center for Clinical Research | Little Rock | Arkansas | 72205 | — |
| Arkansas Clinical Research | Little Rock | Arkansas | 72205 | — |
| Central Cardiology Medical Center | Bakersfield | California | 93308 | — |
| Alliance Clinical | Canoga Park | California | 91303 | — |
| Inland Psychiatric Medical Group | Chino | California | 91710 | — |
| John Muir Physician Network Clinical Research Center | Concord | California | 94520 | — |
| Triallogix | Fullerton | California | 92835 | — |
| Diabetes Lipid Management Center | Huntington Beach | California | 92648 | — |
| University of Calif Irvine Med Cntr | Irvine | California | 92660 | — |
| UC San Diego Health | La Jolla | California | 92037 | — |
| American Institute of Research | Los Angeles | California | 90017 | — |
| Keck Medical Center USC | Los Angeles | California | 90033 | — |
| University of California LA | Los Angeles | California | 90095 | — |
| VA Palo Alto Health Care System | Palo Alto | California | 94304-1207 | — |
| San Diego Veterans Medical Center | San Diego | California | 92161 | — |
| West Coast Research LLC | San Ramon | California | 94582 | — |
| Helping Hands Medical Associates INC | Santa Ana | California | 92704 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Stanford University Medical Center | Stanford | California | 94304 | — |
| Manshadi Heart Institute | Stockton | California | 95204 | — |
| Harbor UCLA Medical Center | Torrance | California | 90502 | — |
| Blue Coast Research Center LLC | Vista | California | 92081 | — |
| Interv Cardiology Med Grp | West Hills | California | 91307 | — |
| Aurora Denver Cardiology Associates | Aurora | Colorado | 80012 | — |
| Rocky Mountain Regional VA Med Ctr | Aurora | Colorado | 80045 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| d-b-a Greenwich Cardio Assoc | Greenwich | Connecticut | 06830 | — |
| Chase Medical Research LLC | Waterbury | Connecticut | 06708 | — |
| Emerson Clinical Research Institute | Washington D.C. | District of Columbia | 20020 | — |
| Excel Medical Clinical Trials LLC | Boca Raton | Florida | 33434 | — |
| Cardiovascular and Vein Center of Florida | Bradenton | Florida | 34209 | — |
| Nova Clinical Research LLC | Bradenton | Florida | 34209 | — |
| Bay Care Medical Group | Clearwater | Florida | 33756 | — |
| Cardiology Research Associates | Daytona Beach | Florida | 32117 | — |
| Hillcrest Medical Research | DeLand | Florida | 32720 | — |
| National Research Institute | Hialeah | Florida | 33013 | — |
| Sister Life Research Inc | Hialeah | Florida | 33013 | — |
| Zenith Clinical Research | Hollywood | Florida | 33021 | — |
| Westside Center for Clinical Research | Jacksonville | Florida | 32205 | — |
| UF Health Science Center | Jacksonville | Florida | 32209 | — |
| Baptist Heart Specialists | Jacksonville Beach | Florida | 32250 | — |
| United Vein and Vascular Centers | Lake Worth | Florida | 33461 | — |
| Infinite Clinical Research | Miami | Florida | 33133 | — |
| A&A Research Group Inc | Miami | Florida | 33186 | — |
| Inpatient Research Clinical LLC | Miami Lakes | Florida | 33014 | — |
| RM Medical Research Inc | Miami Lakes | Florida | 33014 | — |
| Indago Research and Health Ctr Inc | Miami Lakes | Florida | 33016 | — |
| FXM Clin Res Miramar LLC | Miramar | Florida | 33027 | — |
| Advanced Research for Health Improvement LLC | Naples | Florida | 34102 | — |
| Ocala Cardiovascular Research | Ocala | Florida | 34471 | — |
| Oviedo Medical Research | Oviedo | Florida | 32765 | — |
| CTMD Research | Palm Springs | Florida | 33406 | — |
| Broward Research Center | Pembroke Pines | Florida | 33024 | — |
| SEC Clinical Research | Pensacola | Florida | 32503 | — |
| Peace River Cardiovascular Center | Port Charlotte | Florida | 33952 | — |
| Advanced Medical Research Center | St. Petersburg | Florida | 33713 | — |
| New Tampa Health | Tampa | Florida | 33603 | — |
| BayCare Medical Group Inc | Tampa | Florida | 33607 | — |
| James A Haley Veterans Hospital | Tampa | Florida | 33612 | — |
| Genesis Clinical Research | Tampa | Florida | 33614 | — |
| BayCare Health System | Tampa | Florida | 33705 | — |
| Ravessa Clinical Research | Tampa | Florida | 33880 | — |
| Cardiology Partners Clinical Research Institute | Wellington | Florida | 33449 | — |
| Javara Research | Fayetteville | Georgia | 30214 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| Alta Pharmaceutical Research Center | Peachtree Corners | Georgia | 30092 | — |
| Atlanta Heart Specialists LLC | Tucker | Georgia | 30084 | — |
| Solaris Clinical Research | Meridian | Idaho | 83646 | — |
| Saltzer Health | Nampa | Idaho | 83686 | — |
| Biofortis Research | Addison | Illinois | 60101 | — |
| Endeavor Health Clinical Op- NCH | Arlington Heights | Illinois | 60005 | — |
| Cedar Crosse Research Ct | Chicago | Illinois | 60607 | — |
| Chicago Clinical Research Inst | Chicago | Illinois | 60607 | — |
| Gateway Cardiology PC | Jerseyville | Illinois | 62052 | — |
| Methodist Med Center Of Illinois | Peoria | Illinois | 61603 | — |
| SIU School of Medicine | Springfield | Illinois | 62702 | — |
| Prairie Heart Institute | Springfield | Illinois | 62769 | — |
| Elkhart Cardiology Group | Elkhart | Indiana | 46514 | — |
| Franciscan Health Services Research Center | Indianapolis | Indiana | 46237 | — |
| Witham Heart Partners | Lebanon | Indiana | 46052 | — |
| The Heart Center of Lake County | Merrillville | Indiana | 46410 | — |
| Cardiovascular Research Of Northwest Indiana, Llc | Munster | Indiana | 46321 | — |
| Covenant Medical Center | Waterloo | Iowa | 50702 | — |
| University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Midwest Heart and Vascular Spec | Overland Park | Kansas | 66211 | — |
| Cotton O Neil Clinical Res Center | Topeka | Kansas | 66606 | — |
| Ascension Via Christi Research | Wichita | Kansas | 67214 | — |
| University of Kentucky College of Health Sciences | Lexington | Kentucky | 40536 | — |
| U of Louisville Rudd Heart and Lung | Louisville | Kentucky | 40202 | — |
| Christus Health Central Louisiana | Alexandria | Louisiana | 71301 | — |
| Louisiana Cardiology Associates | Baton Rouge | Louisiana | 70808 | — |
| Grace Research LLC | Bossier City | Louisiana | 71111 | — |
| Cardiovascular Associates Research | Covington | Louisiana | 70433 | — |
| Louisiana Heart Center Research | Covington | Louisiana | 70433 | — |
| Avant Research Associates LLC | Crowley | Louisiana | 70526 | — |
| Horizon Research Group of Opelousas LLC | Eunice | Louisiana | 70535 | — |
| Cardiovascular Institute South ASC | Gray | Louisiana | 70359 | — |
| Heart Clinic of Hammond | Hammond | Louisiana | 70403 | — |
| CV Ins of the South | Lafayette | Louisiana | 70503 | — |
| North Shore Heart and Vascular | Mandeville | Louisiana | 70448 | — |
| Clinical Trials Management LLC | Mandeville | Louisiana | 70471 | — |
| Omega Clinical Research | Metairie | Louisiana | 70006 | — |
| Clinical Trials of America LA LLC | Monroe | Louisiana | 71201 | — |
| Barnum Medical Research Inc | Natchitoches | Louisiana | 71457 | — |
| Crescent City Physicians Inc | New Orleans | Louisiana | 70115 | — |
| CV Ins of the South | Opelousas | Louisiana | 70570 | — |
| Grace Research Llc | Shreveport | Louisiana | 71105 | — |
| Louisiana Heart Center Research | Slidell | Louisiana | 70458 | — |
| Southern Clinical Research | Zachary | Louisiana | 70791 | — |
| Sinai Ct for Throm Res and Drug Dev | Baltimore | Maryland | 21209 | — |
| Metropolitan Cardiovascular Consultants Llc | Beltsville | Maryland | 20705 | — |
| Johns Hopkins University | Columbia | Maryland | 21044 | — |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | — |
| Javara Inc | Glenn Dale | Maryland | 20769 | — |
| Capitol Cardiology Associates | Lanham | Maryland | 20706 | — |
| MD Medical Research | Oxon Hill | Maryland | 20745 | — |
| Adventist HealthCare Shady Grove Medical Center | Rockville | Maryland | 20850 | — |
| Tidal Health Peninsula Regional Inc | Salisbury | Maryland | 21804 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| VA Boston Healthcare System | Boston | Massachusetts | 02132 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| ActivMed Practices and Research | Methuen | Massachusetts | 01844 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| AA Medical Research Center | Flint | Michigan | 48504 | — |
| Healthy Heart Cardiology | Grand Rapids | Michigan | 49546 | — |
| McLaren Greater Lansing | Lansing | Michigan | 48910 | — |
| MyMichigan Medical Center Midland | Midland | Michigan | 48670 | — |
| Central Michigan University | Saginaw | Michigan | 48601 | — |
| Providence Hospital Patient Care Research | Southfield | Michigan | 48075 | — |
| Traverse Heart and Vascular | Traverse City | Michigan | 49684 | — |
| Trinity Health Michigan Heart | Ypsilanti | Michigan | 48197 | — |
| St Marys Medical Center | Duluth | Minnesota | 55805 | — |
| University Of Minnesota | Minneapolis | Minnesota | 55455 | — |
| North Memorial Heart and Vascular Institute | Robbinsdale | Minnesota | 55422 | — |
| CentraCare Heart and Vascular Center | Saint Cloud | Minnesota | 56303 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Belzoni Clinical Research | Belzoni | Mississippi | 39038 | — |
| Jackson Heart Clinic | Jackson | Mississippi | 39216 | — |
| VAMC Research-G V Sonny Montgomery Clinic | Jackson | Mississippi | 39216 | — |
| Cardiology Associates of North MS | Tupelo | Mississippi | 38801 | — |
| Yazoo Clinical Research . | Yazoo City | Mississippi | 39194 | — |
| Yazoo Clinical Research | Yazoo City | Mississippi | 39194 | — |
| Kansas City VA Medical Center | Kansas City | Missouri | 64128 | — |
| North Kansas City Hospital | North Kansas City | Missouri | 64116 | — |
| Mercy Hospital | Springfield | Missouri | 65804 | — |
| St Louis V A Medical Center | St Louis | Missouri | 63125-4181 | — |
| Gateway Cardiovascular Rsch Ctr Inc | St Louis | Missouri | 63128 | — |
| Mercy South | St Louis | Missouri | 63128 | — |
| St Louis Heart and Vascular | St Louis | Missouri | 63136 | — |
| Physician Research Collaboration | Lincoln | Nebraska | 68516 | — |
| VA Med NWI Endocrine Studies R151 | Omaha | Nebraska | 68105 | — |
| CCT Research | Omaha | Nebraska | 68130 | — |
| Las Vegas Endocrinology | Henderson | Nevada | 89074 | — |
| AB Clinical Trials | Las Vegas | Nevada | 89119 | — |
| Clinical Research of South Nevada | Las Vegas | Nevada | 89121 | — |
| Catholic Medical Center | Manchester | New Hampshire | 03062 | — |
| Cooper University Health Care | Haddon Heights | New Jersey | 08035 | — |
| New Jersey Heart | Linden | New Jersey | 07036 | — |
| Garden State Heart Care | Manalapan | New Jersey | 07726 | — |
| Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08901 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| The Valley Hospital | Ridgewood | New Jersey | 07450 | — |
| Cardio Metabolic Institute | Somerset | New Jersey | 08873 | — |
| New Mexico Heart Institute | Albuquerque | New Mexico | 87102 | — |
| Albany Medical College | Albany | New York | 12206 | — |
| Meridian Clinical Research | Binghamton | New York | 13901 | — |
| Bassett Medical Center | Cooperstown | New York | 13326 | — |
| Meridian Clinical Research LLC | Endwell | New York | 13760 | — |
| NYU Langone Hlth Card Assoc | Mineola | New York | 11501 | — |
| Weill Cornell Medical Center | New York | New York | 10021 | — |
| Icahn School of Med at Mt Sinai | New York | New York | 10029 | — |
| Northport VA Medical Center | Northport | New York | 11768 | — |
| Rochester Clinical Research | Rochester | New York | 14609 | — |
| State Uni of NY at Stony Brook | Stony Brook | New York | 11794-3362 | — |
| Westchester Medical Center | Valhalla | New York | 10595 | — |
| Novant Health Heart Vas Inst | Charlotte | North Carolina | 28204 | — |
| Tryon Medical Partners PLLC | Charlotte | North Carolina | 28277 | — |
| Lucas Research | Morehead City | North Carolina | 28557 | — |
| NC Heart and Vascular Research LLC | Raleigh | North Carolina | 27607 | — |
| Accellacare of Salisbury | Salisbury | North Carolina | 28144 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Altru Health Research Dept. | Grand Forks | North Dakota | 58201 | — |
| Akron Hospital Summa Health System | Akron | Ohio | 44309 | — |
| Velocity Clin Research Springdale | Cincinnati | Ohio | 45246 | — |
| University Of Cincinnati | Cincinnati | Ohio | 45267 | — |
| Univ Hosp Cleveland Medical Center | Cleveland | Ohio | 44106-5028 | — |
| Premier Cardiovascular Institute | Dayton | Ohio | 45414 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Rama Research LLC | Marion | Ohio | 43302 | — |
| Heart House Research Foundation | Springfield | Ohio | 45504 | — |
| Mercy Health St Vincent Med Ctr | Toledo | Ohio | 43608 | — |
| Oklahoma Heart Institute | Tulsa | Oklahoma | 74133 | — |
| Bend Memorial Clinic | Bend | Oregon | 97701 | — |
| Samaritan Cardiology | Corvallis | Oregon | 97330 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| Independence Health System Cardiovascular Consultants | Butler | Pennsylvania | 16001 | — |
| UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| Preferred Primary Care Physicians | Pittsburgh | Pennsylvania | 15236 | — |
| Preferred Primary Care Physicians | Pittsburgh | Pennsylvania | 15243 | — |
| Frontier Clinical Research LLC | Smithfield | Pennsylvania | 15478 | — |
| Kent County Memorial Hospital | Warwick | Rhode Island | 02886 | — |
| Medical Univ Of South Carolina | Charleston | South Carolina | 29425 | — |
| Columbia Heart Clinic | Columbia | South Carolina | 29203 | — |
| Columbia VA Health Care System | Columbia | South Carolina | 29209 | — |
| Bon Secours Medical Group | Greenville | South Carolina | 29607 | — |
| Prisma Health Upstate | Greenville | South Carolina | 29615 | — |
| Trident Cardiology | Ladson | South Carolina | 29465 | — |
| Family Medicine of Sayebrook | Myrtle Beach | South Carolina | 29588 | — |
| Sanford USD Medical Center | Sioux Falls | South Dakota | 57104 | — |
| North Central Heart | Sioux Falls | South Dakota | 57105 | — |
| Wellmont CVA Heart Institute | Greenville | Tennessee | 37745 | — |
| Apex Cardiology Research Associates of Jackson | Jackson | Tennessee | 38301 | — |
| The Jackson Clinic PA | Jackson | Tennessee | 38301 | — |
| Turkey Creek Medical Center | Knoxville | Tennessee | 37934 | — |
| Accellacare | Knoxville | Tennessee | 37938 | — |
| Memphis Cardiology and Vein Ct | Memphis | Tennessee | 38119 | — |
| Cardiovascular Res of Knoxville LLC | Powell | Tennessee | 37849 | — |
| Tennessee Center For Clinical Trials | Tullahoma | Tennessee | 37388 | — |
| PharmaTex Research LLC | Amarillo | Texas | 79106 | — |
| North Hills Medical Research Inc | Bedford | Texas | 76021 | — |
| Javara Research | Conroe | Texas | 77384 | — |
| VA North Texas Health Care System | Dallas | Texas | 75216 | — |
| Soltero Cardiovascular Research Center | Dallas | Texas | 75226 | — |
| North Texas Endocrine Center | Dallas | Texas | 75231 | — |
| Research Institute of Dallas PA | Dallas | Texas | 75231 | — |
| Texas Health Physicians Group | Dallas | Texas | 75231 | — |
| SW Family Medicine Associates | Dallas | Texas | 75235 | — |
| Alina clinical trials | Dallas | Texas | 78503 | — |
| David Turbay MD PLLC | El Paso | Texas | 79905 | — |
| Texas Health Physicians Group | Fort Worth | Texas | 76104 | — |
| Texas Health Physicians Group | Fort Worth | Texas | 76107 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| UT Physicians Memorial Hermann | Houston | Texas | 77030 | — |
| Orion Medical | Houston | Texas | 77034 | — |
| Village Medical Village MD S Tx | Houston | Texas | 77084 | — |
| FMC Science | Lampasas | Texas | 76550 | — |
| East Texas Research Associates Inc. | Livingston | Texas | 77351 | — |
| CardioVoyage LLC | McKinney | Texas | 75071 | — |
| Discovery Clinical Trials | Pflugerville | Texas | 78660-3015 | — |
| Heartplace-Plano | Plano | Texas | 75075 | — |
| University of Texas Health Science Ctr | San Antonio | Texas | 78229-3900 | — |
| South Texas Cardiovascular Consultants PLLC | San Antonio | Texas | 78229 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | — |
| Sherman Clinical Research | Sherman | Texas | 75090 | — |
| Javara Research | Stephenville | Texas | 76401 | — |
| Privia Medical Group Gulf Coast | Sugar Land | Texas | 77478 | — |
| Progressive Clinical Research | Bountiful | Utah | 84010 | — |
| Burke Internal Medicine and Research | Burke | Virginia | 22015 | — |
| Javara Research | Forest | Virginia | 24551 | — |
| Heart Care Associates P C | Hopewell | Virginia | 23860 | — |
| York Clinical Research | Norfolk | Virginia | 23504 | — |
| Dominion Medical Associates | Richmond | Virginia | 23219 | — |
| Roanoke Heart Institute | Roanoke | Virginia | 24014 | — |
| Winchester Medical Center | Winchester | Virginia | 22601 | — |
| Virginia Mason Medical Centre | Seattle | Washington | 98101 | — |
| Swedish Medical Center-Cardiovascular Research | Seattle | Washington | 98122 | — |
| University of Washington | Seattle | Washington | 98195 | — |
| Universal Research Group LLC | Tacoma | Washington | 98405 | — |
| Confluence Health Hospital | Wenatchee | Washington | 98801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 712 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05030428, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 25, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05030428 live on ClinicalTrials.gov.