LYR-220 for Adult Subjects With Chronic Rhinosinusitis (BEACON Study)
Public ClinicalTrials.gov record NCT05035654. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
BEACON: A Phase II, Patient-blinded, Two-part, Randomized, Parallel-group Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of LYR-220 in Chronic Rhinosinusitis (CRS) Patients Who Have Had a Prior Ethmoidectomy
Study identification
- NCT ID
- NCT05035654
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Lyra Therapeutics
- Industry
- Enrollment
- 48 participants
Conditions and interventions
Interventions
- LYR-220 Design 1 (Part 1 only) Drug
- LYR-220 Design 2 (Part 1 and Part 2) Drug
- Bilateral sham procedure control (Part 2) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 22, 2021
- Primary completion
- Aug 29, 2023
- Completion
- Aug 29, 2023
- Last update posted
- Dec 16, 2024
2021 – 2023
United States locations
- U.S. sites
- 22
- U.S. states
- 13
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Lyra Investigational Site | Carlsbad | California | 92008 | — |
| Lyra Investigational Site | La Mesa | California | 91942 | — |
| Lyra Investigational Site | Roseville | California | 95661 | — |
| Lyra Investigational Site | Torrance | California | 90501 | — |
| Lyra Investigational Site | Chicago | Illinois | 60208 | — |
| Lyra Investigational Site | Chicago | Illinois | 60657 | — |
| Lyra Investigational Site | New Albany | Indiana | 47150 | — |
| Lyra Investigational Site | Louisville | Kentucky | 40205 | — |
| Lyra Investigational Site | Marrero | Louisiana | 70072 | — |
| Lyra Investigational Site | Baltimore | Maryland | 21204 | — |
| Lyra Investigational Site | New Hyde Park | New York | 11042 | — |
| Lyra Investigational Site | New York | New York | 10016 | — |
| Lyra Investigational Site | Chapel Hill | North Carolina | 27599 | — |
| Lyra Investigational Site | Winston-Salem | North Carolina | 27103 | — |
| Lyra Investigational Site | Bethlehem | Pennsylvania | 18017 | — |
| Lyra Investigational Site | Orangeburg | South Carolina | 29118 | — |
| Lyra Investigational Site | Spartanburg | South Carolina | 29303 | — |
| Lyra Investigational Site | Fort Worth | Texas | 76109 | — |
| Lyra Investigational Site | McKinney | Texas | 75069 | — |
| Lyra Investigational Site | San Antonio | Texas | 78258 | — |
| Lyra Investigational Site | South Ogden | Utah | 84405 | — |
| Lyra Investigational Site | Spokane | Washington | 99201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05035654, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 16, 2024 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05035654 live on ClinicalTrials.gov.