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Recruiting Phase 1Phase 2 Interventional

COAST Therapy in Advanced Solid Tumors and Prostate Cancer

ClinicalTrials.gov ID: NCT05036226

Public ClinicalTrials.gov record NCT05036226. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 19, 2026, 10:50 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Combination of Autophagy Selective Therapeutics (COAST) in Advanced Solid Tumors or Relapsed Prostate Cancer, A Phase I/II Trial

Study identification

NCT ID
NCT05036226
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Medical University of South Carolina
Other
Enrollment
76 participants

Conditions and interventions

Interventions

  • Hydroxychloroquine, Metformin, Sirolimus Combination Product
  • Hydroxychloroquine, Metformin, Sirolimus, Dasatanib Combination Product
  • Hydroxychloroquine, Metformin, Sirolimus, Nelfinavir Combination Product
  • Hydroxychloroquine, Metformin, Sirolimus, Nelfinavir, Dasatinib Combination Product

Combination Product

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 2, 2022
Primary completion
May 20, 2027
Completion
May 20, 2028
Last update posted
May 12, 2026

2022 – 2028

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Medical University of South Carolina Charleston South Carolina 29425 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05036226, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 12, 2026 · Synced May 19, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05036226 live on ClinicalTrials.gov.

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