A Study to Evaluate the Efficacy and Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
Public ClinicalTrials.gov record NCT05037929. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IIb, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Astegolimab in Patients With Chronic Obstructive Pulmonary Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy, safety, and pharmacokinetics of astegolimab in combination with standard of care chronic obstructive pulmonary disease (COPD) maintenance therapy in patients with COPD who are former or current smokers and have a history of frequent exacerbations.
Study identification
- NCT ID
- NCT05037929
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 1,334 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 5, 2021 (Actual)
- Primary completion
- Feb 24, 2025 (Actual)
- Completion
- Jul 7, 2025 (Actual)
- Last update posted
- Oct 16, 2026
2021 – 2025
United States locations
- U.S. sites
- 36
- U.S. states
- 14
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| SEC Clinical Research LLC - Dothan 2 - ClinEdge - PPDS | Dothan | Alabama | 36305 | — |
| Jasper Summit Research LLC | Jasper | Alabama | 35501 | — |
| Pulmonary Associates of Mobile PC | Mobile | Alabama | 36608-3135 | — |
| Cadena Care Institute, LLC | Poway | California | 92064-2021 | — |
| Inst. of Healthcare Assessment, Inc. | San Diego | California | 92120 | — |
| Allianz Research Institute Inc | Westminster | California | 92683 | — |
| St. Francis Sleep | Clearwater | Florida | 33765 | — |
| Clinical Site Partners - Leesburg Suite 101 - HyperCore - PPDS | Leesburg | Florida | 34748-5077 | — |
| Pulmonary Specialists of the Palm Beaches | Loxahatchee Groves | Florida | 33470-9206 | — |
| Florida Institute for Clinical Research, LLC | Orlando | Florida | 32825-4454 | — |
| Clinical Site Partners - Winter Park - HyperCore - PPDS | Winter Park | Florida | 32789-4681 | — |
| Northwestern Center for Clinical Research | Chicago | Illinois | 60611 | — |
| Medisphere Medical Research Center, Llc | Evansville | Indiana | 47714 | — |
| Exordia Medical Research, Inc. | Fall River | Massachusetts | 20723 | — |
| Northern Pines Health Center PC | Buckley | Michigan | 49620 | — |
| Revive Research Institute | Lathrup Village | Michigan | 48076 | — |
| Oakland Medical Research | Troy | Michigan | 48085 | — |
| Cardio-Pulmonary Associates | Chesterfield | Missouri | 63017-3627 | — |
| Blessing Health Hannibal | Hannibal | Missouri | 63401 | — |
| Midwest Chest Consultants | Saint Charles | Missouri | 63301 | — |
| CARE Clinical Research | St Louis | Missouri | 63141-6823 | — |
| Midwest Clinical Research LLC | St Louis | Missouri | 63141 | — |
| Sierra Clinical Research - ClinEdge - PPDS | Las Vegas | Nevada | 89106-4159 | — |
| American Health Research Inc. | Charlotte | North Carolina | 28277 | — |
| Clinical Research of Gastonia | Gastonia | North Carolina | 28054-7481 | — |
| Carolina Research Center | Shelby | North Carolina | 28150-3803 | — |
| Southeastern Research Center | Winston-Salem | North Carolina | 27103-4029 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Lowcountry Lung and Critical Care | North Charleston | South Carolina | 29406 | — |
| Clinical Research of Rock Hill | Rock Hill | South Carolina | 29732-1160 | — |
| Velocity Clinical Research Spartanburg PPDS | Spartanburg | South Carolina | 29303-4225 | — |
| South Texas Medical Research Institute, Inc., dba TTS Research ? ClinEdge ? PPDS | Boerne | Texas | 78006-1993 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Metroplex Pulmonology & Sleep Center | McKinney | Texas | 75069 | — |
| Sherman Clinical Research - ClinEdge - PPDS | Sherman | Texas | 75092 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22903-2980 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 157 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05037929, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2026 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05037929 live on ClinicalTrials.gov.