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ClinicalTrials.gov record
Active, not recruiting Phase 3 Interventional

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

ClinicalTrials.gov ID: NCT05047172

Public ClinicalTrials.gov record NCT05047172. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary goal of the trial is to determine if the experimental arms (rivaroxaban or ticagrelor or both) are superior to the clopidogrel arm for lowering the 1-year rate of ischemic stroke, intracerebral hemorrhage, or vascular death.

Study identification

NCT ID
NCT05047172
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
University of Florida
Other
Enrollment
1,683 participants

Conditions and interventions

Eligibility (public fields only)

Age range
30 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 2, 2022 (Actual)
Primary completion
Jan 31, 2027 (Estimated)
Completion
Jan 31, 2027 (Estimated)
Last update posted
Oct 13, 2026

2022 – 2027

United States locations

U.S. sites
114
U.S. states
35
U.S. cities
92
Facility City State ZIP Site status
University of Alabama Hospital Birmingham Alabama 35233 —
University of South Alabama University Hospital Mobile Alabama 36604 —
St. Joseph's Hospital and Medical Center Phoenix Arizona 85013 —
Mercy San Juan Medical Center Carmichael California 95608 —
The Neuron Clinic - Chula Vista Chula Vista California 91910 —
Kaiser Permanente Fontana Medical Center Fontana California 92335 —
Long Beach Memorial Medical Center Long Beach California 90806 —
Los Alamitos Medical Center Los Alamitos California 90720 —
Kaiser Permanente Los Angeles Medical Center Los Angeles California 90027 —
Ronald Reagan UCLA Medical Center, Los Angeles, CA Los Angeles California 90095 —
UC Irvine Medical Center Orange California 92868 —
UC Davis Medical Center Sacramento California 95817 —
Salinas Valley Memorial Hospital Salinas California 93901 —
UCSD Medical Center - Hillcrest Hospital San Diego California 92103 —
Providence Little Company of Mary Medical Center Torrance Torrance California 90503 —
University of Colorado Hospital Aurora Colorado 80045 —
St. Mary's Medical Center Grand Junction Colorado 81501 —
Hartford Hospital Hartford Connecticut 06102 —
Yale New Haven Hospital New Haven Connecticut 06520 —
MedStar Washington Hospital Center Washington D.C. District of Columbia 20010 —
Morton Plant Hospital Clearwater Florida 33756 —
UF Health Shands Hospital Gainesville Florida 32608 —
Baptist Medical Center Jacksonville Jacksonville Florida 32207 —
Mayo Clinic Jacksonville Florida 32224 —
Jackson Memorial Hospital Miami Florida 33136 —
Cleveland Clinic Tradition Hospital Port Saint Lucie Florida 34987 —
Tampa General Hospital Tampa Florida 33606 —
Emory University Hospital Atlanta Georgia 30303 —
Grady Memorial Hospital Atlanta Georgia 30303 —
Augusta University Medical Center Augusta Georgia 30912 —
Memorial Hospital of Carbondale Carbondale Illinois 62901 —
Rush University Medical Center Chicago Illinois 60612 —
University of Illinois Hospital Chicago Illinois 60612 —
University of Chicago Medical Center Chicago Illinois 60637 —
Evanston Hospital Evanston Illinois 60201 —
Advocate Christ Medical Center Oak Lawn Illinois 60453 —
Javon Bea Hospital - Riverside Rockford Illinois 61114 —
University of Kansas Hospital Kansas City Kansas 66160 —
Baptist Health Lexington Lexington Kentucky 40503 —
University of Kentucky Hospital Lexington Kentucky 40536 —
Ochsner Medical Center - Main Campus New Orleans Louisiana 70121 —
University of Maryland Medical Center Baltimore Maryland 21201 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Brigham and Women's Hospital Boston Massachusetts 02115 —
Boston Medical Center Boston Massachusetts 02118 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
UMass Memorial Medical Center Worcester Massachusetts 01655 —
Henry Ford Hospital Detroit Michigan 48202 —
McLaren Flint Flint Michigan 48532 —
McLaren Macomb Mount Clemens Michigan 48043 —
Metro Health Hospital Wyoming Michigan 49519 —
M Health Fairview Southdale Hospital Edina Minnesota 55414 —
Abbott Northwestern Hospital Minneapolis Minnesota 55407 —
M Health Fairview University of Minnesota Medical Center Minneapolis Minnesota 55415 —
University of Mississippi Medical Center Jackson Mississippi 39216 —
University of Missouri Health Care Columbia Missouri 65212 —
Barnes Jewish Hospital St Louis Missouri 62269 —
University of Nebraska Medical Center Omaha Nebraska 68198 —
Cooper University Hospital Camden New Jersey 08103 —
Jersey Shore University Medical Center Neptune City New Jersey 07753 —
Valley Hospital Ridgewood New Jersey 07450 —
University of New Mexico Hospital Albuquerque New Mexico 87106 —
Kings County Hospital Center Brooklyn New York 11203 —
SUNY Downstate Medical Center Brooklyn New York 11203 —
NYU Langone Hospital - Brooklyn Brooklyn New York 11220 —
Buffalo General Medical Center Buffalo New York 14202 —
North Shore University Hospital Lake Success New York 11042 —
NYP Weill Cornell Medical Center New York New York 10021 —
The Mount Sinai Hospital New York New York 10029 —
NYP Columbia University Medical Center New York New York 10032 —
Strong Memorial Hospital Rochester New York 14642 —
Montefiore Medical Center The Bronx New York 10467 —
Carolinas Medical Center Charlotte North Carolina 28207 —
Duke University Hospital Durham North Carolina 27710 —
Moses H. Cone Memorial Hospital Greensboro North Carolina 27405 —
ECU Health Medical Center Greenville North Carolina 27834 —
Wake Forest Baptist Medical Center Winston-Salem North Carolina 27157 —
Cleveland Clinic Akron General Akron Ohio 44307 —
Good Samaritan Hospital Cincinnati Ohio 45220 —
University of Cincinnati Medical Center Cincinnati Ohio 45267 —
UH Cleveland Medical Center Cleveland Ohio 44106 —
Cleveland Clinic Cleveland Ohio 44195 —
OSU Wexner Medical Center Columbus Ohio 43210 —
Toledo Hospital Toledo Ohio 43606 —
Mercy St. Vincent Medical Center Toledo Ohio 43608 —
OU Medical Center Oklahoma City Oklahoma 73104 —
Providence St. Vincent Medical Center Portland Oregon 97225 —
Oregon Health & Science University Hospital Portland Oregon 97239 —
Jefferson Abington Hospital Abington Pennsylvania 19001 —
UPMC Altoona Altoona Pennsylvania 16601 —
UPMC Hamot Erie Pennsylvania 16550 —
Hospital of the University of Pennsylvania Philadelphia Pennsylvania 19104 —
Thomas Jefferson University Hospital Philadelphia Pennsylvania 19107 —
Temple University Hospital, Philadelphia Philadelphia Pennsylvania 19140 —
UPMC Presbyterian Hospital Pittsburgh Pennsylvania 15213 —
Rhode Island Hospital Providence Rhode Island 02903 —
Medical University of South Carolina University Hospital Charleston South Carolina 29425 —
Prisma Health Richland Hospital Columbia South Carolina 29203 —
Prisma Health Greenville Memorial Hospital Greenville South Carolina 29605 —
Methodist University Hospital Memphis Tennessee 38104 —
University of Texas Medical Branch Galveston Texas 77555 —
Houston Methodist Hospital Houston Texas 77030 —
Memorial Hermann Texas Medical Center Houston Texas 77030 —
Covenant Medical Center Lubbock Texas 79410 —
Medical City Plano Plano Texas 75075 —
University of Texas Health Science Center San Antonio San Antonio Texas 78229 —
UT Health Tyler Tyler Texas 75708 —
The University of Vermont Medical Center Burlington Vermont 05401 —
UVA Medical Center Charlottesville Virginia 22903 —
Inova Fairfax Hospital Falls Church Virginia 22042 —
Carilion Roanoke Memorial Hospital Roanoke Virginia 24011 —
Harborview Medical Center Seattle Washington 98104 —
Swedish Medical Center - Cherry Hill Campus Seattle Washington 98122 —
University of Wisconsin University Hospital Madison Wisconsin 53792 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05047172, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 13, 2026 · Synced Oct 19, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05047172 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →