A Study of a Potential Oral Treatment to Prevent COVID-19 in Adults Who Are Exposed to Household Member(s) With a Confirmed Symptomatic COVID-19 Infection
Public ClinicalTrials.gov record NCT05047601. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2/3, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, PLACEBO CONTROLLED STUDY TO EVALUATE THE SAFETY AND EFFICACY OF 2 REGIMENS OF ORALLY ADMINISTERED PF 07321332/RITONAVIR IN PREVENTING SYMPTOMATIC SARS-COV-2 INFECTION IN ADULT HOUSEHOLD CONTACTS OF AN INDIVIDUAL WITH SYMPTOMATIC COVID-19
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this clinical trial is to learn whether the study medicine prevent symptoms of COVID-19 in adults who have been exposed to household member(s) with a confirmed symptomatic COVID-19 infection. All participants in the study will receive treatment for COVID-19 as needed, based on their regular doctor's recommendation. Two-thirds of participants will also receive two study medicines (PF-07321332 and ritonavir) by mouth twice a day for either five or ten days. We will compare the experiences of people receiving the study medicines to those of the people who do not. This will help us determine if the study medicines are safe and effective
Study identification
- NCT ID
- NCT05047601
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 2,954 participants
Conditions and interventions
Conditions
Interventions
- PF-07321332 Drug
- Placebo for PF-07321332 Drug
- Placebo for Ritonavir Drug
- Ritonavir Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 9, 2021 (Actual)
- Primary completion
- Apr 12, 2022 (Actual)
- Completion
- Apr 12, 2022 (Actual)
- Last update posted
- May 6, 2023
2021 – 2022
United States locations
- U.S. sites
- 64
- U.S. states
- 12
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Research Inc | Pelham | Alabama | 35124 | — |
| The Institute for Liver Health dba Arizona Clinical Trials | Tucson | Arizona | 85712 | — |
| Ascada Health PC | Fullerton | California | 92835 | — |
| Optimus Medical Group | San Francisco | California | 94102 | — |
| Synergy Healthcare | Bradenton | Florida | 34208 | — |
| MOORE Clinical Research, Inc. | Brandon | Florida | 33511 | — |
| TrueBlue Clinical Research | Brandon | Florida | 33511 | — |
| Herco Medical and Research Center Inc | Coral Gables | Florida | 33134 | — |
| Advance Clinical Research Group | Cutler Bay | Florida | 33157 | — |
| Beautiful Minds Clinical Research Center | Cutler Bay | Florida | 33157 | — |
| Qway Research | Hialeah | Florida | 33010 | — |
| Eastern Research Inc | Hialeah | Florida | 33013 | — |
| Inpatient Research Clinic | Hialeah | Florida | 33013 | — |
| Doral Medical Research,LLC | Hialeah | Florida | 33016 | — |
| Unlimited Medical Research Group, LLC | Hialeah Gardens | Florida | 33018 | — |
| ASCLEPES Research Centers | Lutz | Florida | 33549 | — |
| Angels Clinical Research Institute | Miami | Florida | 33122 | — |
| LCC Medical Research Institute, LLC | Miami | Florida | 33126 | — |
| Premium Medical Research Corp | Miami | Florida | 33126 | — |
| Global Health Clinical Trials Corp | Miami | Florida | 33135 | — |
| South Florida Research Center, Inc. | Miami | Florida | 33135 | — |
| University of Miami Health System | Miami | Florida | 33136 | — |
| I.V.A.M. Clinical & Investigational Center, LLC | Miami | Florida | 33144 | — |
| Medical Research of Westchester Inc | Miami | Florida | 33165 | — |
| C'A Research | Miami | Florida | 33174 | — |
| ProLive Medical Research, Corp. | Miami | Florida | 33175 | — |
| Entrust Clinical Research | Miami | Florida | 33176 | — |
| Reed Medical Research | Miami | Florida | 33176 | — |
| Kendall South Medical Center, Inc. | Miami | Florida | 33185 | — |
| Clinical Site Partners, Inc dba CSP Miami | Miami | Florida | 33186 | — |
| Coral Research Clinic Corp | Miami | Florida | 33186 | — |
| Pro-Care Research Center, Corp. | Miami Gardens | Florida | 33014 | — |
| Savin Medical Group, LLC | Miami Lakes | Florida | 33014 | — |
| Omega Research Orlando | Orlando | Florida | 32808 | — |
| NAPA Research LLC | Pompano Beach | Florida | 33064 | — |
| CDC Research Institute, LLC | Port Saint Lucie | Florida | 34952 | — |
| USPA Advance Concept Medical Research Group LLC | South Miami | Florida | 33143 | — |
| ASCLEPES Research Centers | Spring Hill | Florida | 34609 | — |
| GCP, Global Clinical Professionals | St. Petersburg | Florida | 33705 | — |
| Sunrise Research Institute | Sunrise | Florida | 33325 | — |
| Santos Research Center, CORP | Tampa | Florida | 33615 | — |
| Research by Design, LLC | Chicago | Illinois | 60643 | — |
| Accellacare | Ames | Iowa | 50010 | — |
| McFarland Clinic, PC | Ames | Iowa | 50010 | — |
| Southern Clinical Research Associates. LLC | Metairie | Louisiana | 70001 | — |
| Meridian Clinical Research, LLC | Grand Island | Nebraska | 68803 | — |
| Quality Clinical Research Inc | Omaha | Nebraska | 68112 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| Walmart | Las Vegas | Nevada | 89108 | — |
| Excel Clinical research | Las Vegas | Nevada | 89109 | — |
| Walgreens | Las Vegas | Nevada | 89121 | — |
| NYC Health + Hospitals / Harlem | New York | New York | 10037 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Innovo Research: Wilmington Health | Wilmington | North Carolina | 28401 | — |
| PharmaTex Research, LLC | Amarillo | Texas | 79109 | — |
| Conroe Willis Medical Research | Conroe | Texas | 77304 | — |
| South Texas Clinical Research | Corpus Christi | Texas | 78413 | — |
| SingnatureCare Emergency Center | Houston | Texas | 77008 | — |
| Trio Clinical Trials, LLC | Houston | Texas | 77008 | — |
| C & R Research Services USA | Houston | Texas | 77022 | — |
| SMS Clinical Research, LLC | Mesquite | Texas | 75149 | — |
| Epic Medical Research | Red Oak | Texas | 75154 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
| Tranquility Research | Webster | Texas | 77598 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 106 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05047601, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2023 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05047601 live on ClinicalTrials.gov.