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Completed Phase 2Phase 3 Interventional Results available

A Study of a Potential Oral Treatment to Prevent COVID-19 in Adults Who Are Exposed to Household Member(s) With a Confirmed Symptomatic COVID-19 Infection

ClinicalTrials.gov ID: NCT05047601

Public ClinicalTrials.gov record NCT05047601. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 12:53 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 2/3, RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, PLACEBO CONTROLLED STUDY TO EVALUATE THE SAFETY AND EFFICACY OF 2 REGIMENS OF ORALLY ADMINISTERED PF 07321332/RITONAVIR IN PREVENTING SYMPTOMATIC SARS-COV-2 INFECTION IN ADULT HOUSEHOLD CONTACTS OF AN INDIVIDUAL WITH SYMPTOMATIC COVID-19

Study identification

NCT ID
NCT05047601
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
2,954 participants

Conditions and interventions

Conditions

Interventions

  • PF-07321332 Drug
  • Placebo for PF-07321332 Drug
  • Placebo for Ritonavir Drug
  • Ritonavir Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 8, 2021
Primary completion
Apr 11, 2022
Completion
Apr 11, 2022
Last update posted
May 5, 2023

2021 – 2022

United States locations

U.S. sites
64
U.S. states
12
U.S. cities
39
Facility City State ZIP Site status
Cahaba Research Inc Pelham Alabama 35124
The Institute for Liver Health dba Arizona Clinical Trials Tucson Arizona 85712
Ascada Health PC Fullerton California 92835
Optimus Medical Group San Francisco California 94102
Synergy Healthcare Bradenton Florida 34208
MOORE Clinical Research, Inc. Brandon Florida 33511
TrueBlue Clinical Research Brandon Florida 33511
Herco Medical and Research Center Inc Coral Gables Florida 33134
Advance Clinical Research Group Cutler Bay Florida 33157
Beautiful Minds Clinical Research Center Cutler Bay Florida 33157
Qway Research Hialeah Florida 33010
Eastern Research Inc Hialeah Florida 33013
Inpatient Research Clinic Hialeah Florida 33013
Doral Medical Research,LLC Hialeah Florida 33016
Unlimited Medical Research Group, LLC Hialeah Gardens Florida 33018
ASCLEPES Research Centers Lutz Florida 33549
Angels Clinical Research Institute Miami Florida 33122
LCC Medical Research Institute, LLC Miami Florida 33126
Premium Medical Research Corp Miami Florida 33126
Global Health Clinical Trials Corp Miami Florida 33135
South Florida Research Center, Inc. Miami Florida 33135
University of Miami Health System Miami Florida 33136
I.V.A.M. Clinical & Investigational Center, LLC Miami Florida 33144
Medical Research of Westchester Inc Miami Florida 33165
C'A Research Miami Florida 33174
ProLive Medical Research, Corp. Miami Florida 33175
Entrust Clinical Research Miami Florida 33176
Reed Medical Research Miami Florida 33176
Kendall South Medical Center, Inc. Miami Florida 33185
Clinical Site Partners, Inc dba CSP Miami Miami Florida 33186
Coral Research Clinic Corp Miami Florida 33186
Pro-Care Research Center, Corp. Miami Gardens Florida 33014
Savin Medical Group, LLC Miami Lakes Florida 33014
Omega Research Orlando Orlando Florida 32808
NAPA Research LLC Pompano Beach Florida 33064
CDC Research Institute, LLC Port Saint Lucie Florida 34952
USPA Advance Concept Medical Research Group LLC South Miami Florida 33143
ASCLEPES Research Centers Spring Hill Florida 34609
GCP, Global Clinical Professionals St. Petersburg Florida 33705
Sunrise Research Institute Sunrise Florida 33325
Santos Research Center, CORP Tampa Florida 33615
Research by Design, LLC Chicago Illinois 60643
Accellacare Ames Iowa 50010
McFarland Clinic, PC Ames Iowa 50010
Southern Clinical Research Associates. LLC Metairie Louisiana 70001
Meridian Clinical Research, LLC Grand Island Nebraska 68803
Quality Clinical Research Inc Omaha Nebraska 68112
Quality Clinical Research Omaha Nebraska 68114
Walmart Las Vegas Nevada 89108
Excel Clinical research Las Vegas Nevada 89109
Walgreens Las Vegas Nevada 89121
NYC Health + Hospitals / Harlem New York New York 10037
Monroe Biomedical Research Monroe North Carolina 28112
Innovo Research: Wilmington Health Wilmington North Carolina 28401
PharmaTex Research, LLC Amarillo Texas 79109
Conroe Willis Medical Research Conroe Texas 77304
South Texas Clinical Research Corpus Christi Texas 78413
SingnatureCare Emergency Center Houston Texas 77008
Trio Clinical Trials, LLC Houston Texas 77008
C & R Research Services USA Houston Texas 77022
SMS Clinical Research, LLC Mesquite Texas 75149
Epic Medical Research Red Oak Texas 75154
Sun Research Institute San Antonio Texas 78215
Tranquility Research Webster Texas 77598

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 106 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05047601, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 5, 2023 · Synced Apr 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05047601 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →