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Terminated Phase 2 Interventional

ITIL-168 in Advanced Melanoma

ClinicalTrials.gov ID: NCT05050006

Public ClinicalTrials.gov record NCT05050006. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 5:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Open-label, Multicenter Study Evaluating the Safety and Efficacy of Autologous Tumor-infiltrating Lymphocytes (TILs) in Subjects With Advanced Melanoma (DELTA-1)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

DELTA-1 is a phase 2 clinical trial to evaluate the efficacy and safety of ITIL-168 in adult subjects with advanced melanoma who have previously been treated with a PD-1 inhibitor. ITIL-168 is a cell therapy derived from a patient's own tumor-infiltrating immune cells (lymphocytes; TILs).

Study identification

NCT ID
NCT05050006
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Instil Bio
Industry
Enrollment
29 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 6, 2021
Primary completion
Feb 26, 2023
Completion
Feb 26, 2023
Last update posted
Apr 15, 2024

2021 – 2023

United States locations

U.S. sites
20
U.S. states
11
U.S. cities
17
Facility City State ZIP Site status
University of California San Diego, Moores Cancer Center La Jolla California 92093
The Angeles Clinic and Research Institute Los Angeles California 90025
USC - Norris Comprehensive Cancer Center Los Angeles California 90033
UCLA Health - Westwood Cancer Care Los Angeles California 90095
Stanford Cancer Institute Stanford California 94305
University of Colorado - Anschutz Cancer Pavilion Aurora Colorado 80045
Georgetown University Medical Center Washington D.C. District of Columbia 20007
The University of Miami - Sylvester Comprehensive Cancer Center Miami Florida 33136
Orlando Health Cancer Institute Orlando Florida 32806
Moffitt Cancer Center Tampa Florida 33612
Rush University Cancer Center Chicago Illinois 60612
Loyola University Chicago Maywood Illinois 60153
University of Louisville, James Graham Brown Cancer Center Louisville Kentucky 40202
Massachusetts General Hospital Boston Massachusetts 02114
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
University of Minnesota, Masonic Cancer Center Minneapolis Minnesota 55455
Atlantic Health System - Morristown Medical Center Morristown New Jersey 07962
Cleveland Clinic - Taussig Cancer Center Cleveland Ohio 44195
St. Luke's University Health Network Bethlehem Pennsylvania 18015
Fox Chase Cancer Center Philadelphia Pennsylvania 19111

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05050006, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 15, 2024 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05050006 live on ClinicalTrials.gov.

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