A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia
Public ClinicalTrials.gov record NCT05056727. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, International, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on CKD Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia
Study identification
- NCT ID
- NCT05056727
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 1,112 participants
Conditions and interventions
Conditions
Interventions
- Sodium Zirconium Cyclosilicate (SZC) Drug
- Placebo Drug
- Lisinopril Drug
- Valsartan Drug
- Irbesartan Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 130 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 29, 2021
- Primary completion
- Feb 6, 2024
- Completion
- Feb 6, 2024
- Last update posted
- Jan 7, 2026
2021 – 2024
United States locations
- U.S. sites
- 42
- U.S. states
- 20
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Surprise | Arizona | 85374 | — |
| Research Site | Tucson | Arizona | 85741 | — |
| Research Site | Canyon Country | California | 91351 | — |
| Research Site | Chula Vista | California | 91910 | — |
| Research Site | Northridge | California | 91324 | — |
| Research Site | San Dimas | California | 91773 | — |
| Research Site | South Gate | California | 90280 | — |
| Research Site | Tarzana | California | 91356 | — |
| Research Site | Denver | Colorado | 80230 | — |
| Research Site | Boynton Beach | Florida | 33435 | — |
| Research Site | Hialeah | Florida | 33012 | — |
| Research Site | Lauderdale Lakes | Florida | 33313 | — |
| Research Site | Ocoee | Florida | 34761 | — |
| Research Site | Temple Terrace | Florida | 33637 | — |
| Research Site | Nampa | Idaho | 83687 | — |
| Research Site | Chicago | Illinois | 60643 | — |
| Research Site | Oak Brook | Illinois | 60523 | — |
| Research Site | Fort Wayne | Indiana | 46804 | — |
| Research Site | Louisville | Kentucky | 40205 | — |
| Research Site | Boston | Massachusetts | 02114 | — |
| Research Site | Boston | Massachusetts | 02115 | — |
| Research Site | Flint | Michigan | 48532 | — |
| Research Site | Saint Clair Shores | Michigan | 48081 | — |
| Research Site | Columbia | Missouri | 65201 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | Albuquerque | New Mexico | 87109 | — |
| Research Site | Albany | New York | 12205 | — |
| Research Site | Great Neck | New York | 11021 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Cincinnati | Ohio | 45267 | — |
| Research Site | Bethlehem | Pennsylvania | 18017 | — |
| Research Site | Chester | Pennsylvania | 19013 | — |
| Research Site | Columbia | South Carolina | 29203 | — |
| Research Site | Orangeburg | South Carolina | 29118 | — |
| Research Site | Chattanooga | Tennessee | 37404 | — |
| Research Site | Arlington | Texas | 76015 | — |
| Research Site | Fort Worth | Texas | 76164 | — |
| Research Site | Houston | Texas | 77004 | — |
| Research Site | Houston | Texas | 77054 | — |
| Research Site | Houston | Texas | 77099 | — |
| Research Site | San Antonio | Texas | 78212 | — |
| Research Site | Newport News | Virginia | 23606 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 234 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05056727, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 7, 2026 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05056727 live on ClinicalTrials.gov.