A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy
Public ClinicalTrials.gov record NCT05059223. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multi- Center Study to Assess the Efficacy and Safety of AXS-12 in the Treatment of Cataplexy and Excessive Daytime Sleepiness in Subjects With Narcolepsy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a multi-center, double-blind, placebo-controlled, randomized Phase 3 trial to assess the safety and efficacy of AXS-12 in narcoleptic subjects with cataplexy and excessive daytime sleepiness (EDS).
Study identification
- NCT ID
- NCT05059223
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 90 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 15 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 15, 2021 (Actual)
- Primary completion
- Mar 15, 2024 (Actual)
- Completion
- Mar 15, 2024 (Actual)
- Last update posted
- May 28, 2026
2021 – 2024
United States locations
- U.S. sites
- 47
- U.S. states
- 22
- U.S. cities
- 46
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Site | Alabaster | Alabama | 35007 | — |
| Clinical Research Site | Peoria | Arizona | 85381 | — |
| Clinical Research Site | Phoenix | Arizona | 85054 | — |
| Clinical Research Site | Redwood City | California | 94063 | — |
| Clinical Research Site | San Diego | California | 92103 | — |
| Clinical Research Site | Santa Ana | California | 92705 | — |
| Clinical Research Site | Santa Monica | California | 90404 | — |
| Clinical Research Site | Boulder | Colorado | 80301 | — |
| Clinical Research Site | Colorado Springs | Colorado | 80918 | — |
| Clinical Research Site | Brandon | Florida | 33511 | — |
| Clinical Research Site | Clearwater | Florida | 33765 | — |
| Clinical Research Site | Doral | Florida | 33122 | — |
| Clinical Research Site | Kissimmee | Florida | 34741 | — |
| Clinical Research Site | Miami | Florida | 33176 | — |
| Clinical Research Site | Miami Lakes | Florida | 33016 | — |
| Clinical Research Site | St. Petersburg | Florida | 33707 | — |
| Clinical Research Site | Tampa | Florida | 33634 | — |
| Clinical Research Site | Winter Park | Florida | 32789 | — |
| Clinical Research Site | Atlanta | Georgia | 30315 | — |
| Clinical Research Site | Atlanta | Georgia | 30328 | — |
| Clinical Research Site | Gainesville | Georgia | 30501 | — |
| Clinical Research Site | Macon | Georgia | 31210 | — |
| Clinical Research Site | Stockbridge | Georgia | 30281 | — |
| Clinical Research Site | Honolulu | Hawaii | 96817 | — |
| Clinical Research Site | Peoria | Illinois | 61637 | — |
| Clinical Research Site | Fort Wayne | Indiana | 46804 | — |
| Clinical Research Site | Chevy Chase | Maryland | 20815 | — |
| Clinical Research Site | Newton | Massachusetts | 02459 | — |
| Clinical Research Site | North Dartmouth | Massachusetts | 02747 | — |
| Clinical Research Site | Kalamazoo | Michigan | 49008 | — |
| Clinical Research Site | Novi | Michigan | 48377 | — |
| Clinical Research Site | St Louis | Missouri | 63123 | — |
| Clinical Research Site | Las Vegas | Nevada | 89106 | — |
| Clinical Research Site | Neptune City | New Jersey | 07753 | — |
| Clinical Research Site | Brooklyn | New York | 11230 | — |
| Clinical Research Site | New Hyde Park | New York | 11040 | — |
| Clinical Research Site | Denver | North Carolina | 28037 | — |
| Clinical Research Site | Gastonia | North Carolina | 28054 | — |
| Clinical Research Site | Huntersville | North Carolina | 28078 | — |
| Clinical Research Site | Cincinnati | Ohio | 45245 | — |
| Clinical Research Site | Wyomissing | Pennsylvania | 19610 | — |
| Clinical Research Site | Charleston | South Carolina | 29425 | — |
| Clinical Research Site | Columbia | South Carolina | 29201 | — |
| Clinical Research Site | Austin | Texas | 78731 | — |
| Clinical Research Site | San Antonio | Texas | 78229 | — |
| Clinical Research Site | Sugar Land | Texas | 77478 | — |
| Clinical Research Site | Williamsburg | Virginia | 23188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05059223, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 28, 2026 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05059223 live on ClinicalTrials.gov.