A Study to Evaluate THR-687 Treatment for Diabetic Macular Oedema.
Public ClinicalTrials.gov record NCT05063734. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomised, Multicentre Study to Assess the Dose Level of Multiple THR-687 Injections and to Evaluate the Efficacy and Safety of THR-687 Versus Aflibercept for the Treatment of Diabetic Macular Oedema (DME)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is conducted to select the THR-687 dose level (Part A of the study) and to assess the efficacy and safety of the selected dose level compared to aflibercept (Part B of the study).
Study identification
- NCT ID
- NCT05063734
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 16 participants
Conditions and interventions
Interventions
- THR-687 dose level 1 Drug
- THR-687 dose level 2 Drug
- THR-687 selected dose level Drug
- Aflibercept Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 27, 2021 (Actual)
- Primary completion
- Jun 29, 2022 (Actual)
- Completion
- Jun 29, 2022 (Actual)
- Last update posted
- Aug 18, 2023
2021 – 2022
United States locations
- U.S. sites
- 18
- U.S. states
- 10
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Salehi Retina Institute Inc. | Huntington Beach | California | 92647 | — |
| California Eye Specialists Medical Group, Inc. | Pasadena | California | 91107 | — |
| Retinal Consultants Medical Group | Sacramento | California | 95825 | — |
| Retina Consultants of Southern Colorado, P.C. | Colorado Springs | Colorado | 80909 | — |
| Retina Associates, Ltd | Elmhurst | Illinois | 60126 | — |
| University Retina and macula Associates, PC | Oak Forest | Illinois | 60452 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Retina Vitreous Surgeons of Central New York, PC | Liverpool | New York | 13088 | — |
| Tulsa Retina Consultants | Tulsa | Oklahoma | 74114 | — |
| Eye Care Specialists | Kingston | Pennsylvania | 18704 | — |
| Tennessee Retina, PC | Nashville | Tennessee | 37203 | — |
| Austin Research Center of Retina | Austin | Texas | 78705 | — |
| Retina Consultants of Texas | Katy | Texas | 77494 | — |
| Valley Retina Institute, P.A. | McAllen | Texas | 78503 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Retina Center of Texas | Southlake | Texas | 76092 | — |
| Strategic Clinical Research Group | Willow Park | Texas | 76087 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05063734, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 18, 2023 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05063734 live on ClinicalTrials.gov.