ClinicalTrials.gov record
Assessment of CCM in HF With Higher Ejection Fraction
ClinicalTrials.gov ID: NCT05064709
Public ClinicalTrials.gov record NCT05064709. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 8, 2026, 8:09 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Assessment of Implantable CCM in the Heart Failure Group With Higher Ejection Fraction
Study identification
- NCT ID
- NCT05064709
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- Impulse Dynamics
- Industry
- Enrollment
- 1,500 participants
Conditions and interventions
Conditions
Interventions
- Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System Device
- OPTIMIZER™ Smart Mini System Device
Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 2, 2022
- Primary completion
- Jan 31, 2029
- Completion
- Jan 31, 2029
- Last update posted
- May 5, 2026
2022 – 2029
United States locations
- U.S. sites
- 105
- U.S. states
- 31
- U.S. cities
- 82
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Grandview Medical Group Research, LLC | Birmingham | Alabama | 35243 | Recruiting |
| CardioVascular Associates of Mesa | Mesa | Arizona | 85206 | Recruiting |
| Chan Heart Rhythm Institute | Mesa | Arizona | 85206 | Recruiting |
| Southwest Cardiovascular Associates | Mesa | Arizona | 85208 | Recruiting |
| Arizona Heart Rhythm | Phoenix | Arizona | 85016 | Recruiting |
| Cardiovascular Consultants, Ltd | Phoenix | Arizona | 85032 | Recruiting |
| HonorHealth | Scottsdale | Arizona | 85258 | Recruiting |
| Pima Heart and Vascular | Tuscon | Arizona | 85712 | Recruiting |
| John Muir Health | Concord | California | 94520 | Recruiting |
| University of California San Diego | La Jolla | California | 92093 | Recruiting |
| USC Keck School of Medicine | Los Angeles | California | 90033 | Recruiting |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| Valley Clinical Trials- Northridge | Northridge | California | 91325 | Recruiting |
| Sequoia Hospital | Redwood City | California | 94062 | Recruiting |
| University of California Davis Health | Sacramento | California | 95817 | Withdrawn |
| University of California, San Francisco | San Francisco | California | 94143 | Withdrawn |
| Nuvance Health - Danbury Hospital | Danbury | Connecticut | 06810 | Recruiting |
| Hartford Healthcare | Hartford | Connecticut | 06103 | Recruiting |
| HCA Florida JFK Hospital | Atlantis | Florida | 33462 | Recruiting |
| Nouvelle Clinical Research LLC | Cutler Bay | Florida | 33189 | Recruiting |
| Broward Health | Fort Lauderdale | Florida | 33316 | Recruiting |
| Memorial Healthcare System | Hollywood | Florida | 33021 | Withdrawn |
| Baptist Health South Florida | Miami | Florida | 33176 | Recruiting |
| NCA Research Institute - Florida | Naples | Florida | 34102 | Withdrawn |
| AdventHealth Orlando | Orlando | Florida | 32803 | Recruiting |
| Revival Clinical Research | Orlando | Florida | 32807 | Recruiting |
| Tallahassee Research Institute | Tallahassee | Florida | 32308 | Withdrawn |
| Cleveland Clinic Foundation - Florida Weston Hospital | Weston | Florida | 33326 | Recruiting |
| Piedmont Healthcare | Atlanta | Georgia | 30309 | Withdrawn |
| Franciscan Health Indianapolis | Indianapolis | Indiana | 46237 | Withdrawn |
| Ascension Medical Group St. Vincent | Indianapolis | Indiana | 46260 | Recruiting |
| University of Iowa | Iowa City | Iowa | 52242 | Recruiting |
| MercyOne Iowa Heart | West Des Moines | Iowa | 50266 | Recruiting |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | Recruiting |
| Kansas City Cardiac Arrhythmia Research LLC | Overland Park | Kansas | 66211 | Recruiting |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | Recruiting |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | Withdrawn |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| University of Michigan | Ann Arbor | Michigan | 48113 | Recruiting |
| Henry Ford St. John Hospital | Detroit | Michigan | 48236 | Recruiting |
| Ascension Providence Hospital | Southfield | Michigan | 48075 | Recruiting |
| Trinity health- Michigan Heart | Ypsilanti | Michigan | 48197 | Recruiting |
| Minneapolis Heart Institute at Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | Recruiting |
| North Mississippi Medical Center | Tupelo | Mississippi | 38801 | Withdrawn |
| St. Louis Heart and Vascular | Bridgeton | Missouri | 63044 | Recruiting |
| St. Luke's Hospital | Chesterfield | Missouri | 63017 | Withdrawn |
| St. Lukes Hospital Kansas City (Mid America Heart Institute) | Kansas City | Missouri | 64111 | Recruiting |
| Bryan Heart | Lincoln | Nebraska | 68506 | Recruiting |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198-5331 | Withdrawn |
| Catholic Medical Center | Manchester | New Hampshire | 03102 | Withdrawn |
| Our Lady of Lourdes | Camden | New Jersey | 08103 | Recruiting |
| Hackensack University Medical Center | Edison | New Jersey | 08837 | Withdrawn |
| Jersey Shore University Medical Center | Edison | New Jersey | 08837 | Withdrawn |
| Cooper Hospital- Cardiovascular Associates of Delaware Valley | Haddon Heights | New Jersey | 08035 | Recruiting |
| Atlantic Health System- Morristown Medical Center | Morristown | New Jersey | 07960 | Recruiting |
| Rutgers New Jersey Medical School | Piscataway | New Jersey | 08854 | Withdrawn |
| AtlantiCare Regional Medical Center | Pomona | New Jersey | 08240 | Recruiting |
| Buffalo General | Buffalo | New York | 14203 | Recruiting |
| Weill Cornell Medicine | New York | New York | 10021 | Withdrawn |
| Nuvance Health - Heart & Vascular Institute/Hudson Valley Cardiovascular Practice, PC | Poughkeepsie | New York | 12601 | Recruiting |
| Nuvance Health - Vassar brothers Medical Center | Poughkeepsie | New York | 12601 | Recruiting |
| Sanger Heart and Vascular | Charlotte | North Carolina | 28203 | Withdrawn |
| TriHealth Bethesda | Cincinnati | Ohio | 45202 | Withdrawn |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | Withdrawn |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | Recruiting |
| Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | Recruiting |
| OhioHealth Research Institute | Columbus | Ohio | 43214 | Recruiting |
| Mercy Health- St. Vincent Medical Center LLC | Toledo | Ohio | 43608 | Withdrawn |
| Oklahoma Heart Institute | Tulsa | Oklahoma | 74104 | Recruiting |
| St. Francis Hospital - Tulsa | Tulsa | Oklahoma | 74136 | Recruiting |
| Providence Heart & Vascular | Portland | Oregon | 97225 | Recruiting |
| Bryn Mawr Medical Specialists Association | Bryn Mawr | Pennsylvania | 19010 | Recruiting |
| UPMC Pinnacle Harrisburg | Harrisburg | Pennsylvania | 17110 | Withdrawn |
| Penn State Hershey Medical City | Hershey | Pennsylvania | 17033 | Recruiting |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17602 | Withdrawn |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104-6061 | Recruiting |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | Recruiting |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | Recruiting |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | Recruiting |
| Tower Health Reading Hospital | Reading | Pennsylvania | 19611 | Withdrawn |
| WellSpan Health | York | Pennsylvania | 17403 | Withdrawn |
| Prisma Health Upstate | Greenville | South Carolina | 29601 | Recruiting |
| Bon Secours Upstate Cardiology | Greenville | South Carolina | 29607 | Withdrawn |
| North Central Heart | Sioux Falls | South Dakota | 57108 | Recruiting |
| The Stern Cardiovascular Foundation | Germantown | Tennessee | 38138 | Recruiting |
| Texas Cardiac Arrhythmia Research Foundation | Austin | Texas | 78705 | Withdrawn |
| Ascension Seton | Austin | Texas | 78723 | Recruiting |
| Austin Heart | Austin | Texas | 78756 | Recruiting |
| Baylor Scott and White Research Institute | Dallas | Texas | 75204 | Recruiting |
| HCA Medical City Dallas | Dallas | Texas | 75230 | Withdrawn |
| Baylor Scott White- All Saints- Fort Worth | Fort Worth | Texas | 76104 | Recruiting |
| Medical City Fort Worth Hospital | Fort Worth | Texas | 76104 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Recruiting |
| Houston Methodist | Houston | Texas | 77030 | Recruiting |
| Memorial Hermann Texas Medical Center | Houston | Texas | 77030 | Recruiting |
| Heart Rhythm Specialists | McKinney | Texas | 75070 | Recruiting |
| Baylor Scott and White- The Heart Hospital- Plano | Plano | Texas | 75093 | Withdrawn |
| Baylor Scott and White Research Institute - Round Rock | Round Rock | Texas | 78665 | Recruiting |
| Methodist Hospital | San Antonio | Texas | 78229 | Withdrawn |
| Bon Secours St. Mary's | Richmond | Virginia | 23114 | Recruiting |
| Bon Secours St. Mary's | Richmond | Virginia | 23226 | Recruiting |
| Swedish Medical Center | Seattle | Washington | 98122 | Recruiting |
| Peace Health | Vancouver | Washington | 98664 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05064709, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05064709 live on ClinicalTrials.gov.