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Terminated Phase 3 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Non-proliferative Diabetic Retinopathy (NPDR)

ClinicalTrials.gov ID: NCT05066230

Public ClinicalTrials.gov record NCT05066230. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 7:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Prospective, Randomized, Double-masked, Sham-controlled, Multicenter, Two-arm Phase3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Participants With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This Phase 3 Study will evaluate the efficacy and safety of KSI-301 in participants with moderately severe to severe non-proliferative diabetic retinopathy (NPDR).

Study identification

NCT ID
NCT05066230
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Kodiak Sciences Inc
Industry
Enrollment
253 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 6, 2021
Primary completion
Aug 2, 2023
Completion
Aug 30, 2023
Last update posted
Sep 4, 2024

2021 – 2023

United States locations

U.S. sites
46
U.S. states
21
U.S. cities
45
Facility City State ZIP Site status
Retinal Research Institute, LLC Phoenix Arizona 85014
Retina Vitreous Associates Beverly Hills California 90211
Retina Consultants of Orange County Fullerton California 92835
Retina Consultants of Southern California Redlands California 92374
Retinal Consultants Medical Group Inc Sacramento California 95825
California Retina Consultants - Santa Maria Santa Maria California 93454
Connecticut Eye Consultants Danbury Connecticut 06810
Retina Group of New England Waterford Connecticut 06385
The Macula Center/ Blue Ocean Clinical Research Clearwater Florida 33761
Retina Group of Florida Fort Lauderdale Florida 33308
Florida Eye Associates Melbourne Florida 32901
Med Eye Associates Miami Florida 33143
Florida Retina Institute Orlando Florida 32806
Center for Retina & Macular Disease Winter Haven Florida 33880
Southeast Retina Center Augusta Georgia 30909
Retina Specialists of Idaho Boise Idaho 83713
University of Chicago Chicago Illinois 60637
Springfield Clinic LLP Springfield Illinois 62703
Retina Associates PA Lenexa Kansas 66215
Cumberland Valley Retina Consultants PC Hagerstown Maryland 21740
Foundation for Vision Research Grand Rapids Michigan 49525
Sierra Eye Associates Reno Nevada 89502
Envision Ocular LLC Bloomfield New Jersey 07003
Long Island Vitreoretinal Consultants Hauppauge New York 11788
Ophthalmic Consultants of Long Island Oceanside New York 11572
Graystone Eye Hickory North Carolina 28603-2588
Cascade Medical Research Institute Eugene Oregon 97401
MidAtlantic Retina Bethlehem Pennsylvania 18017-9412
Charleston Neurosciences Institute Beaufort South Carolina 29902
Charleston Neuroscience Center Charleston South Carolina 29414
Southeastern Retina Associates PC Knoxville Tennessee 37909
Charles Retina Institute Memphis Tennessee 38119-4823
Tennessee Retina PC Nashville Tennessee 37203
Retina Research Institute of Texas Abilene Texas 79606
Panhandle Eye Group, LLP Amarillo Texas 79106
Austin Retina Associates Austin Texas 78705
Retina Consultants of Texas (Houston) Bellaire Texas 77401
Star Vision Consultants Burleson Texas 76028
Retina Consultants of Texas (Katy) Katy Texas 77494
Texas Retina Associates Plano Texas 75075
Austin Retina Associates (Round Rock) Round Rock Texas 78681
Medical Center Ophthalmology Associates San Antonio Texas 78240
Retina Consultants of San Antonio San Antonio Texas 78240
Retina Consultants of Texas - (Woodlands) The Woodlands Texas 77384
Piedmont Eye Center Lynchburg Virginia 24502
Spokane Eye Spokane Washington 99204

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05066230, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 4, 2024 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05066230 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →