ST266 Eyedrops for the Treatment of Persistent Corneal Epithelial Defects
Public ClinicalTrials.gov record NCT05066698. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study With Open-Label Extension to Evaluate the Safety and Efficacy of ST266 Eye Drops in the Treatment of Persistent Corneal Epithelial Defects
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective is to determine the efficacy of ST266 eye drops in healing persistent epithelial defects (PED). After 8 weeks of randomized, double-blind treatment, non-healers will enter into an additional 8-week open-label ST266 treatment period. All patients will be followed for 3-months post-treatment for monitoring of safety and maintenance of re-epithelialization.
Study identification
- NCT ID
- NCT05066698
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 8 participants
Conditions and interventions
Conditions
Interventions
- ST266 Biological
- 0.67% Sodium Chloride Ophthalmic Solution Other
- Open-label ST266 Biological
Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 27, 2022 (Actual)
- Primary completion
- Sep 7, 2022 (Actual)
- Completion
- Sep 7, 2022 (Actual)
- Last update posted
- Oct 25, 2022
2022
United States locations
- U.S. sites
- 31
- U.S. states
- 17
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Trinity Research Group | Dothan | Alabama | 36301 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Atlantis Eye Care | Huntington Beach | California | 92647 | — |
| UCLA Stein Eye Institute | Los Angeles | California | 90095 | — |
| Stanford | Palo Alto | California | 94303 | — |
| UCLA Doheny Eye Center | Pasadena | California | 91105 | — |
| California Eye Specialists Medical Group | Pasadena | California | 91107 | — |
| Bowden Eye & Associates | Jacksonville | Florida | 32259 | — |
| Shettle Eye Research | Largo | Florida | 33733 | — |
| Millennium Clinical Research, Inc | Miami | Florida | 33125 | — |
| MedEye Associates | Miami | Florida | 33143 | — |
| Cincinnati Eye Institute | Edgewood | Kentucky | 41017 | — |
| University of Maryland Eye Associates | Baltimore | Maryland | 21201 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts Eye and Ear | Boston | Massachusetts | 02114 | — |
| Mercy Clinic Eye Specialists- Ophthalmology | Springfield | Missouri | 65804 | — |
| UNMC Truhlsen Eye Institute | Omaha | Nebraska | 68105 | — |
| UNC Kittner Eye Center | Chapel Hill | North Carolina | 27517 | — |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | — |
| OSU Wexner Medical Center | Columbus | Ohio | 43212 | — |
| Ophthalmic Partners, PC | Bala-Cynwyd | Pennsylvania | 19004 | — |
| Vanderbilt Eye Institute | Nashville | Tennessee | 37232 | — |
| Houston Eye Associates | Houston | Texas | 77025 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Blanton Eye Institute/Houston Methodist Eye Associates | Houston | Texas | 77030 | — |
| Texas Eye Research Center | Hurst | Texas | 76054 | — |
| R and R Eye Research, LLC | San Antonio | Texas | 78229 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 34502 | — |
| WVU Eye Institute | Morgantown | West Virginia | 26505 | — |
| The Eye Centers of Racine and Kenosha | Kenosha | Wisconsin | 53142 | — |
| University of Wisconsin | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05066698, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 25, 2022 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05066698 live on ClinicalTrials.gov.