A Pivotal Safety and Efficacy Study of OCS-01 Eye Drops in Participants With Diabetic Macular Edema (DIAMOND 1)
Public ClinicalTrials.gov record NCT05066997. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3 Double-Masked, Randomized, 2 Stage, Multicenter Study of the Efficacy and Safety of OCS-01 Eye Drops in Subjects With Diabetic Macular Edema
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to evaluate the efficacy and safety of the topical ophthalmic administration of OCS- 01 as compared to Vehicle in participants with Diabetic Macular Edema (DME).
Study identification
- NCT ID
- NCT05066997
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 552 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 19, 2021 (Actual)
- Primary completion
- Apr 10, 2026 (Actual)
- Completion
- Apr 10, 2026 (Actual)
- Last update posted
- May 5, 2026
2021 – 2026
United States locations
- U.S. sites
- 40
- U.S. states
- 20
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Retina and Vitreous Consultants | Phoenix | Arizona | 85016 | — |
| Phoenix Retina Associates | Phoenix | Arizona | 85050 | — |
| Retina Partners of Northwest Arkansas | Springdale | Arkansas | 72764 | — |
| Retina-Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Retinal Consultants Medical Group | Modesto | California | 95356 | — |
| California Eye Specialists Medical Group | Pasadena | California | 91107 | — |
| California Eye Specialists Medical Group | Redlands | California | 92373 | — |
| Retina Consultants of Southern California | Redlands | California | 92374 | — |
| California Retina Consultants | Santa Maria | California | 93454 | — |
| Retina Group Of New England | Waterford | Connecticut | 06385 | — |
| Rand Eye Institute | Deerfield Beach | Florida | 33064 | — |
| Florida Retina Institute | Jacksonville | Florida | 32216 | — |
| MedEye Associates | Miami | Florida | 33143 | — |
| Florida Retina Institute | Orlando | Florida | 32806 | — |
| Retina Care Specialists | Palm Beach Gardens | Florida | 33410 | — |
| East Florida Eye Institute | Stuart | Florida | 34994 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Retina Associates | Elmhurst | Illinois | 60126 | — |
| University Retina | Lemont | Illinois | 60439 | — |
| Midwest Eye Institute | Carmel | Indiana | 46290 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Retina Consultants of Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| The Retina Institute | St Louis | Missouri | 63128 | — |
| Retina-Vitreous Surgeons of Central New York | Liverpool | New York | 13088 | — |
| North Carolina Retina Associates | Wake Forest | North Carolina | 27587 | — |
| Velocity (Meridian) Clinical Research | Cincinnati | Ohio | 45202 | — |
| Verum Research LLC | Eugene | Oregon | 97401 | — |
| Vision Research Solutions in Philadelphia | Philadelphia | Pennsylvania | 19141 | — |
| Retina Consultants of Charleston | Beaufort | South Carolina | 29902 | — |
| Charleston Neuroscience Institute | Ladson | South Carolina | 29456 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Retina Consultants of Austin/Austin Research Center for Retina | Austin | Texas | 78705 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Retina Center of Texas | Grapevine | Texas | 76051 | — |
| Valley Retina Institute PA d.b.a. Gulf Coast Eye Institute | McAllen | Texas | 78503 | — |
| Tyler Retina Consultants | Tyler | Texas | 75703 | — |
| Strategic Clinical Research Group | Willow Park | Texas | 76087 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05066997, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05066997 live on ClinicalTrials.gov.