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Completed Phase 2 Interventional Results available

IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC

ClinicalTrials.gov ID: NCT05077709

Public ClinicalTrials.gov record NCT05077709. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 8:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Multi-Arm (Basket) Trial Investigating the Safety and Efficacy of IO102-IO103 in Combination With Pembrolizumab, as First-Line Treatment for Patients With Metastatic NSCLC, SCCHN, or Metastatic mUBC

Study identification

NCT ID
NCT05077709
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
IO Biotech
Industry
Enrollment
63 participants

Conditions and interventions

Interventions

  • IO102-IO103 in combination with pembrolizumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 10, 2022
Primary completion
Nov 29, 2025
Completion
Feb 7, 2026
Last update posted
Apr 7, 2026

2022 – 2026

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
9
Facility City State ZIP Site status
City of Hope Duarte California 91010
UC Davis Cancer Center Sacramento California 95817
University of California San Diego San Diego California 92093
Mid Florida Hematology and Oncology Center Orange City Florida 32763
Montefiore Medical Center The Bronx New York 10467
University of Toledo Medical Center Toledo Ohio 43614
Oregon Health & Science University Portland Oregon 97239
University of Pennsylvania Philadelphia Pennsylvania 19104
Virginia Cancer Specialists Fairfax Virginia 22031

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05077709, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 7, 2026 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05077709 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →