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Terminated Phase 1 Interventional

A Study Evaluating the Safety, Pharmacokinetics, and Preliminary Efficacy of Orally Administered SM08502 Combined With Hormonal Therapy or Chemotherapy in Subjects With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT05084859

Public ClinicalTrials.gov record NCT05084859. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 13, 2026, 10:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b, Open-Label, Dose-Escalation, Dose-Expansion Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Orally Administered SM08502 Combined With Hormonal Therapy or Chemotherapy in Subjects With Advanced Solid Tumors

Study identification

NCT ID
NCT05084859
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Biosplice Therapeutics, Inc.
Industry
Enrollment
30 participants

Conditions and interventions

Interventions

  • Abiraterone Drug
  • Docetaxel Drug
  • FOLFIRI Protocol Drug
  • Panitumumab Drug
  • Prednisone Drug
  • SM08502 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 2, 2021
Primary completion
Oct 19, 2022
Completion
Oct 19, 2022
Last update posted
Aug 8, 2024

2021 – 2022

United States locations

U.S. sites
16
U.S. states
12
U.S. cities
14
Facility City State ZIP Site status
The University of Arizona Cancer Center (UACC) - North Campus Tucson Arizona 85719-1478
University of Colorado, Anschutz Aurora Colorado 80045-2571
University of Colorado Aurora Colorado 80045
Maine Center for Cancer Medicine Scarborough Maine 04074-7172
START Midwest Grand Rapids Michigan 49546
Memorial Sloan-Kettering Cancer Center New York New York 10021-0005
Duke Cancer Institute (DCI) - Duke Cancer Center Durham North Carolina 27710-2000
The Carl and Edyth Lindner Center for Research and Education at The Christ Hospital, LLC Cincinnati Ohio 45219
Vanderbilt University Nashville Tennessee 37212
Texas Oncology Fort Worth Texas 76104
Texas Oncology-San Antonio Northeast San Antonio Texas 78217
UT Health San Antonio - Mays Cancer Center - Institute for Drug Development San Antonio Texas 78229
START Mountain Region West Valley City Utah 84119
Virginia Cancer Specialists, PC Fairfax Virginia 20176
Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care Roanoke Virginia 24014
Seattle Cancer Care Alliance (SCCA) Seattle Washington 98109-1023

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05084859, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 8, 2024 · Synced May 13, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05084859 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →