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Active, not recruiting Phase 2 Interventional

Preventing High Blood Sugar in People Being Treated for Metastatic Breast Cancer

ClinicalTrials.gov ID: NCT05090358

Public ClinicalTrials.gov record NCT05090358. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 6:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Targeting Insulin Feedback to Enhance Alpelisib (TIFA): A Phase 2 Randomized Control Trial in Metastatic PIK3CA-mutant Hormone-Receptor Positive Breast Cancer

Study identification

NCT ID
NCT05090358
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Enrollment
15 participants

Conditions and interventions

Interventions

  • Ketogenic Diet Dietary Supplement
  • Low Carbohydrate Diet Dietary Supplement
  • Alpelisib Drug
  • Fulvestrant Drug
  • Canagliflozin Drug

Dietary Supplement · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 7, 2021
Primary completion
Oct 7, 2026
Completion
Oct 7, 2026
Last update posted
Oct 26, 2025

2021 – 2026

United States locations

U.S. sites
9
U.S. states
3
U.S. cities
8
Facility City State ZIP Site status
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) Basking Ridge New Jersey 07920
Memorial Sloan Kettering Monmouth (Limited Protocol Activities) Middletown New Jersey 07748
Memorial Sloan Kettering Bergen (Limited Protocol Activities) Montvale New Jersey 07645
Memorial Sloan Kettering Suffolk - Commack (Limited protocol activity) Commack New York 11725
Memorial Sloan Kettering Westchester (All protocol Activities) Harrison New York 10604
Memorial Sloan Kettering Cancer Center New York New York 10065
Weill Cornell Medical College (Data Collection & Data Analysis) New York New York 10065
Memorial Sloan Kettering Nassau (Limited Protocol Activities) Uniondale New York 11553
Ohio State University (Data Collection & Data Analysis) Columbus Ohio 43210

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05090358, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 26, 2025 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05090358 live on ClinicalTrials.gov.

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