ClinicalTrials.gov record
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
ClinicalTrials.gov ID: NCT05099770
Public ClinicalTrials.gov record NCT05099770. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized Controlled Study of Renal Autologous Cell Therapy (REACT) in Subjects With Type 2 Diabetes and Chronic Kidney Disease (REGEN-006)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the safety and efficacy of up to 2 REACT/rilparencel injections in participants with T2DM and CKD.
Study identification
- NCT ID
- NCT05099770
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 685 participants
Conditions and interventions
Conditions
Interventions
- Renal Autologous Cell Therapy (REACT/ rilparencel) Biological
- Sham Comparator Procedure
Biological · Procedure
Eligibility (public fields only)
- Age range
- 30 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 4, 2022
- Primary completion
- Nov 30, 2029
- Completion
- Nov 30, 2029
- Last update posted
- Aug 10, 2026
2022 – 2029
United States locations
- U.S. sites
- 75
- U.S. states
- 26
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Nephrology Consultants | Huntsville | Alabama | 35805 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| Amicis Research Center | Beverly Hills | California | 90211 | — |
| Kidney Consultants Medical Group | Granada Hills | California | 91344 | — |
| IMD Clinical Trials | Huntington Park | California | 90255 | — |
| Advanced Medical Research, LLC | Lakewood | California | 90712 | — |
| Medicine and Nephrology Associates | Los Alamitos | California | 90720 | — |
| Academic Medical Research Institute | Los Angeles | California | 90022 | — |
| Southern California Hospital | Los Angeles | California | 90095 | — |
| Allameh Medical Corporation | Mission Viejo | California | 92691 | — |
| Golden Pacific Nephrology Medical Clinic Inc | Monterey Park | California | 91755 | — |
| Northridge Kidney Care Center | Northridge | California | 91324 | — |
| Valley Renal Medical Group | Northridge | California | 91324 | — |
| Valley Clinical Trials | Northridge | California | 91325 | — |
| Integrity Medical Discovery | Pico Rivera | California | 90660 | — |
| National Institute of Clinical Research | Pomona | California | 91768 | — |
| Nephrology Associates Medical Group | Riverside | California | 92505 | — |
| UC Davis Medical Group GI Unit | Sacramento | California | 95817 | — |
| North America Research Institute | San Dimas | California | 91773 | — |
| Henry Mayo Newhall Hospital | Valencia | California | 91355 | — |
| Nephrology Associates PA | Newark | Delaware | 19713 | — |
| West Broward Research Institute | Coral Springs | Florida | 33313 | — |
| Florida Kidney Physicians | Fort Lauderdale | Florida | 33316 | — |
| South Fort Lauderdale Nephrology | Fort Lauderdale | Florida | 33316 | — |
| University of Florida | Gainesville | Florida | 32608 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Ethos Palm Beach | Loxahatchee Groves | Florida | 33470 | — |
| Global Clinix, LLC | Miami | Florida | 33155 | — |
| Professional Research Center, Inc. | Miami | Florida | 33172 | — |
| New Phase Clinical Trials | Miami Beach | Florida | 33140 | — |
| Infigo Clinical Research | Sanford | Florida | 32771 | — |
| Genesis Clinical Research | Tampa | Florida | 33603 | — |
| American Clinical Trials | Acworth | Georgia | 30101 | — |
| Wellstar Health System | Augusta | Georgia | 30912 | — |
| Boise Kidney and Hypertension PLLC | Boise | Idaho | 83706 | — |
| Care Institute | Chubbuck | Idaho | 83202 | — |
| Insight Hospital & Medical Center Chicago | Chicago | Illinois | 60616 | — |
| The University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| Indiana Nephrology | Fishers | Indiana | 46037 | — |
| Fresenius Kidney Care Mishawaka | Mishawaka | Indiana | 46545 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Nephrology Associates of Lexington | Lexington | Kentucky | 40504 | — |
| LSU Health Sciences Center | Shreveport | Louisiana | 71103 | — |
| Washington Nephrology Associates | Takoma Park | Maryland | 20854 | — |
| Holyoke Medical Center | Springfield | Massachusetts | 01107 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Nephrology Center, PC | Kalamazoo | Michigan | 49007 | — |
| St. Clair Nephrology Research | Roseville | Michigan | 48066 | — |
| Southwest MS Nephrology | Brookhaven | Mississippi | 39601 | — |
| Nephrology Associates | Columbus | Mississippi | 39705 | — |
| Nephrology and Hypertension Associates | Tupelo | Mississippi | 38801 | — |
| Seacoast Kidney & Hypertension Specialists | Portsmouth | New Hampshire | 03801 | — |
| NYU Langone | New York | New York | 10017 | — |
| ICAHN School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Jacobi Medical Center | The Bronx | New York | 10461 | — |
| UNC Chapel Hill | Chapel Hill | North Carolina | 27514 | — |
| Lifespan Clinical Research Center | East Providence | Rhode Island | 02915 | — |
| Dunes Clinical Research | Dakota Dunes | South Dakota | 57049 | — |
| Knoxville Kidney Center | Knoxville | Tennessee | 37923 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Pioneer Research Solutions, Inc. | Cypress | Texas | 77429 | — |
| Texas Tech Health Sciences | El Paso | Texas | 79905 | — |
| Texas Tech University Health | El Paso | Texas | 79905 | — |
| Plaza Nephrology | Houston | Texas | 77004 | — |
| Biopharma Informatic, LLC | Houston | Texas | 77043 | — |
| Prolato Clinical Research Center | Houston | Texas | 77054 | — |
| Clinical Research Strategies, Inc | Houston | Texas | 77090 | — |
| United Memorial Medical Center | Houston | Texas | 77091 | — |
| Clinical Advancement Center, PLLC | San Antonio | Texas | 78212 | — |
| University Health System | San Antonio | Texas | 78229 | — |
| Prolato Clinical Research Center - Sugar Land | Sugar Land | Texas | 77479 | — |
| Renal Physicians of Montgomery County | The Woodlands | Texas | 77384 | — |
| Salem VA Medical Center | Salem | Virginia | 24153 | — |
| Providence Medical Research Ctr | Spokane | Washington | 99204 | — |
| University of Wisconsin-Madison | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05099770, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 10, 2026 · Synced Sep 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05099770 live on ClinicalTrials.gov.