Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

ClinicalTrials.gov ID: NCT05099770

Public ClinicalTrials.gov record NCT05099770. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized Controlled Study of Renal Autologous Cell Therapy (REACT) in Subjects With Type 2 Diabetes and Chronic Kidney Disease (REGEN-006)

Study identification

NCT ID: NCT05099770
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Prokidney; Industry
Enrollment: 685 participants

Conditions and interventions

Conditions

Interventions

Renal Autologous Cell Therapy (REACT/ rilparencel) Biological
Sham Comparator Procedure

Biological · Procedure

Eligibility (public fields only)

Age range: 30 Years to 80 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jan 4, 2022
Primary completion: Nov 30, 2029
Completion: Nov 30, 2029
Last update posted: Mar 22, 2026

2022 – 2029

United States locations

U.S. sites: 79
U.S. states: 28
U.S. cities: 66

Facility	City	State	ZIP	Site status
Nephrology Consultants	Huntsville	Alabama	35805	Recruiting
University of Arizona	Tucson	Arizona	85724	Recruiting
Amicis Research Center	Beverly Hills	California	90211	Active, not recruiting
Paradise Clinical Research Group LLC	Glendora	California	91741	Withdrawn
Kidney Consultants Medical Group	Granada Hills	California	91344	Active, not recruiting
IMD Clinical Trials	Huntington Park	California	90255	Recruiting
Advanced Medical Research, LLC	Lakewood	California	90712	Recruiting
Medicine and Nephrology Associates	Los Alamitos	California	90720	Recruiting
Academic Medical Research Institute	Los Angeles	California	90022	Recruiting
Southern California Hospital	Los Angeles	California	90095	Recruiting
Allameh Medical Corporation	Mission Viejo	California	92691	Completed
Golden Pacific Nephrology Medical Clinic Inc	Monterey Park	California	91755	Recruiting
Northridge Kidney Care Center	Northridge	California	91324	Active, not recruiting
Valley Renal Medical Group	Northridge	California	91324	Recruiting
Valley Clinical Trials	Northridge	California	91325	Recruiting
Integrity Medical Discovery	Pico Rivera	California	90660	Active, not recruiting
National Institute of Clinical Research	Pomona	California	91768	Recruiting
Nephrology Associates Medical Group	Riverside	California	92505	Recruiting
UC Davis Medical Group GI Unit	Sacramento	California	95817	Recruiting
North America Research Institute	San Dimas	California	91773	Recruiting
Henry Mayo Newhall Hospital	Valencia	California	91355	Active, not recruiting
Nephrology Associates PA	Newark	Delaware	19713	Recruiting
West Broward Research Institute	Coral Springs	Florida	33313	Active, not recruiting
Florida Kidney Physicians	Fort Lauderdale	Florida	33316	Completed
South Fort Lauderdale Nephrology	Fort Lauderdale	Florida	33316	Recruiting
University of Florida	Gainesville	Florida	32608	Recruiting
Mayo Clinic	Jacksonville	Florida	32224	Recruiting
Ethos Palm Beach	Loxahatchee Groves	Florida	33470	Recruiting
Global Clinix, LLC	Miami	Florida	33155	Recruiting
Professional Research Center, Inc.	Miami	Florida	33172	Recruiting
New Phase Clinical Trials	Miami Beach	Florida	33140	Recruiting
Infigo Clinical Research	Sanford	Florida	32771	Recruiting
Genesis Clinical Research	Tampa	Florida	33603	Completed
American Clinical Trials	Acworth	Georgia	30101	Terminated
Wellstar Health System	Augusta	Georgia	30912	Recruiting
Boise Kidney and Hypertension PLLC	Boise	Idaho	83706	Recruiting
Care Institute	Chubbuck	Idaho	83202	Recruiting
Insight Hospital & Medical Center Chicago	Chicago	Illinois	60616	Recruiting
The University of Chicago Medical Center	Chicago	Illinois	60637	Active, not recruiting
Indiana Nephrology	Fishers	Indiana	46037	Recruiting
Fresenius Kidney Care Mishawaka	Mishawaka	Indiana	46545	Recruiting
University of Iowa	Iowa City	Iowa	52242	Recruiting
Nephrology Associates of Lexington	Lexington	Kentucky	40504	Recruiting
LSU Health Sciences Center	Shreveport	Louisiana	71103	Recruiting
Washington Nephrology Associates	Takoma Park	Maryland	20854	Completed
Holyoke Medical Center	Springfield	Massachusetts	01107	Suspended
University of Michigan	Ann Arbor	Michigan	48109	Recruiting
Nephrology Center, PC	Kalamazoo	Michigan	49007	Recruiting
St. Clair Nephrology Research	Roseville	Michigan	48066	Suspended
Southwest MS Nephrology	Brookhaven	Mississippi	39601	Recruiting
Nephrology Associates	Columbus	Mississippi	39705	Recruiting
Nephrology and Hypertension Associates	Tupelo	Mississippi	38801	Recruiting
Saint Louis University	St Louis	Missouri	63110	Withdrawn
Nevada Kidney Disease & Hypertension Center	Las Vegas	Nevada	89052	Withdrawn
Seacoast Kidney & Hypertension Specialists	Portsmouth	New Hampshire	03801	Recruiting
NYU Langone	New York	New York	10017	Recruiting
ICAHN School of Medicine at Mount Sinai	New York	New York	10029	Recruiting
Jacobi Medical Center	The Bronx	New York	10461	Recruiting
UNC Chapel Hill	Chapel Hill	North Carolina	27514	Recruiting
Lifespan Clinical Research Center	East Providence	Rhode Island	02915	Recruiting
Rhode Island Hospital	Providence	Rhode Island	02903	Withdrawn
Dunes Clinical Research	Dakota Dunes	South Dakota	57049	Recruiting
Knoxville Kidney Center	Knoxville	Tennessee	37923	Recruiting
Vanderbilt University Medical Center	Nashville	Tennessee	37232	Recruiting
Pioneer Research Solutions, Inc.	Cypress	Texas	77429	Recruiting
Texas Tech Health Sciences	El Paso	Texas	79905	Completed
Texas Tech University Health	El Paso	Texas	79905	Active, not recruiting
Plaza Nephrology	Houston	Texas	77004	Recruiting
Biopharma Informatic, LLC	Houston	Texas	77043	Suspended
Prolato Clinical Research Center	Houston	Texas	77054	Recruiting
Clinical Research Strategies, Inc	Houston	Texas	77090	Recruiting
United Memorial Medical Center	Houston	Texas	77091	Recruiting
Clinical Advancement Center, PLLC	San Antonio	Texas	78212	Recruiting
University Health System	San Antonio	Texas	78229	Recruiting
Prolato Clinical Research Center - Sugar Land	Sugar Land	Texas	77479	Recruiting
Renal Physicians of Montgomery County	The Woodlands	Texas	77384	Recruiting
Salem VA Medical Center	Salem	Virginia	24153	Recruiting
Providence Medical Research Ctr	Spokane	Washington	99204	Recruiting
University of Wisconsin-Madison	Madison	Wisconsin	53792	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05099770, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 22, 2026 · Synced May 6, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05099770 live on ClinicalTrials.gov.

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