Olorofim Aspergillus Infection Study
Public ClinicalTrials.gov record NCT05101187. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase III, Adjudicator-blinded, Randomised Study to Evaluate Efficacy and Safety of Treatment With Olorofim Versus Treatment With AmBisome® Followed by Standard of Care in Patients With Invasive Fungal Disease Caused by Aspergillus Species
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).
Study identification
- NCT ID
- NCT05101187
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 225 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 29, 2022 (Actual)
- Primary completion
- Nov 18, 2025 (Actual)
- Completion
- Mar 19, 2026 (Actual)
- Last update posted
- Oct 8, 2026
2022 – 2026
United States locations
- U.S. sites
- 24
- U.S. states
- 19
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | — |
| City of Hope National Medical Center | Duarte | California | 91010 | — |
| University of California Davis Health System | Sacramento | California | 95817 | — |
| UCSF Helen Diller Medical Center at Parnassus Heights | San Francisco | California | 94143 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 64111 | — |
| The Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| NIH Clinical Center ,NIAID,NIH | Bethesda | Maryland | 20892 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Clairvoyant Research Group, LLC | Las Vegas | Nevada | 89119 | — |
| Rutgers RWJMS | New Brunswick | New Jersey | 08901 | — |
| Weill Cornell Medicine NY Presbyterian Hospital | New York | New York | 10065 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27514 | — |
| Duke Department of Medicine Infectious Diseases Division | Durham | North Carolina | 27710 | — |
| OU Health OU Medical Center | Oklahoma City | Oklahoma | 73104 | — |
| University of Pittsburgh Medical Center Health System | Pittsburgh | Pennsylvania | 15232 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109-1024 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 119 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05101187, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 8, 2026 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05101187 live on ClinicalTrials.gov.