First in Human Study of TORL-1-23 in Participants With Advanced Cancer

ClinicalTrials.gov ID: NCT05103683

Public ClinicalTrials.gov record NCT05103683. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 11, 2026, 10:24 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, First in Human, Dose-Escalation Study of TORL-1-23 in Participants With Advanced Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-1-23 in patients with advanced cancer

Study identification

NCT ID: NCT05103683
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1
Lead sponsor: TORL Biotherapeutics, LLC; Industry
Enrollment: 90 participants

Conditions and interventions

Conditions

Interventions

TORL-1-23 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 16, 2021
Primary completion: Aug 30, 2026
Completion: Nov 14, 2026
Last update posted: Feb 12, 2026

2021 – 2026

United States locations

U.S. sites: 9
U.S. states: 7
U.S. cities: 9

Facility	City	State	ZIP	Site status
Providence Medical Foundation	Fullerton	California	92835	Recruiting
UCLA - JCCC Clinical Research Unit	Los Angeles	California	90095	Recruiting
University of Kentucky Medical Center	Lexington	Kentucky	40536	Recruiting
University of Minnesota	Minneapolis	Minnesota	55455	Recruiting
Mayo Clinic in Rochester	Rochester	Minnesota	55905	Recruiting
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Recruiting
Cleveland Clinic	Cleveland	Ohio	44195	Recruiting
Sarah Cannon Research Institute Texas Oncology	Tyler	Texas	75702	Recruiting
Virginia Cancer Specialists	Fairfax	Virginia	22031	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05103683, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Feb 12, 2026 · Synced Sep 11, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05103683 live on ClinicalTrials.gov.

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