A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)
Public ClinicalTrials.gov record NCT05107128. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of this study is to evaluate the effect of SAGE-718 on cognitive performance and functioning in participants with HD.
Study identification
- NCT ID
- NCT05107128
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 189 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 25 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 26, 2022 (Actual)
- Primary completion
- Sep 4, 2024 (Actual)
- Completion
- Oct 3, 2024 (Actual)
- Last update posted
- Sep 15, 2025
2022 – 2024
United States locations
- U.S. sites
- 34
- U.S. states
- 23
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sage Investigational Site | Little Rock | Arkansas | 72205 | — |
| Sage Investigational Site | La Jolla | California | 92037 | — |
| Sage Investigational Site | Los Angeles | California | 90095 | — |
| Sage Investigational Site | Sacramento | California | 95817 | — |
| Sage Investigational Site | Englewood | Colorado | 80113 | — |
| Sage Investigational Site | Washington D.C. | District of Columbia | 20007 | — |
| Sage Investigational Site | Boca Raton | Florida | 33431 | — |
| Sage Investigational Site | Boca Raton | Florida | 33486 | — |
| Sage Investigational Site | Tampa | Florida | 33612 | — |
| Sage Investigational Site | Honolulu | Hawaii | 96817 | — |
| Sage Investigational Site | Chicago | Illinois | 60611 | — |
| Sage Investigational Site | Chicago | Illinois | 60612 | — |
| Sage Investigational Site | Indianapolis | Indiana | 46202 | — |
| Sage Investigational Site | Iowa City | Iowa | 52242 | — |
| Sage Investigational Site | Kansas City | Kansas | 66160 | — |
| Sage Investigational Site | Baltimore | Maryland | 21287 | — |
| Sage Investigational Site | Boston | Massachusetts | 02129 | — |
| Sage Investigational Site | Boston | Massachusetts | 02215 | — |
| Sage Investigational Site | Farmington Hills | Michigan | 48334 | — |
| Sage Investigational Site | Buffalo | New York | 14221 | — |
| Sage Investigational Site | New York | New York | 10032 | — |
| Sage Investigational Site | Chapel Hill | North Carolina | 27599 | — |
| Sage Investigational Site | Durham | North Carolina | 27705 | — |
| Sage Investigational Site | Cincinnati | Ohio | 45219 | — |
| Sage Investigational Site | Toledo | Ohio | 43614 | — |
| Sage Investigational Site | Philadelphia | Pennsylvania | 19107 | — |
| Sage Investigational Site | Charleston | South Carolina | 29425 | — |
| Sage Investigational Site | Memphis | Tennessee | 38157 | — |
| Sage Investigational Site | Nashville | Tennessee | 37212 | — |
| Sage Investigational Site | Houston | Texas | 77030 | — |
| Sage Investigational Site | Richmond | Virginia | 23298 | — |
| Sage Investigational Site | Kirkland | Washington | 98034 | — |
| Sage Investigational Site | Spokane | Washington | 99202 | — |
| Sage Investigational Site | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05107128, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 15, 2025 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05107128 live on ClinicalTrials.gov.