ClinicalTrials.gov record
Screening for High Frequency Malignant Disease
ClinicalTrials.gov ID: NCT05117840
Public ClinicalTrials.gov record NCT05117840. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The SHIELD (Screening for High Frequency Malignant Disease) study is a prospective, observational, multi-site basket design trial without randomization. The primary objective of the study is to evaluate the sensitivity and specificity of a blood-based GuardantLUNAR-2 test to detect high frequency cancer in screen-relevant populations.
Study identification
- NCT ID
- NCT05117840
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 12,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 13, 2022 (Actual)
- Primary completion
- Dec 31, 2026 (Estimated)
- Completion
- Dec 31, 2026 (Estimated)
- Last update posted
- Jul 6, 2026
2022 – 2026
United States locations
- U.S. sites
- 125
- U.S. states
- 28
- U.S. cities
- 108
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama Birmingham Lung Health Center | Birmingham | Alabama | 35233 | — |
| Highlands Oncology Group PA | Fayetteville | Arkansas | 72703 | — |
| Pacific Cancer Medical Center | Anaheim | California | 92801 | — |
| Providence St. Joseph Hospital Eureka Cancer Program | Eureka | California | 95501 | — |
| SoCal Clinical Research | Fountain Valley | California | 92708 | — |
| Advanced Investigative Medicine | Hawthorne | California | 90250 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| California Medical Research Associates Inc. | Northridge | California | 91324 | — |
| Providence Medical Foundation | Santa Rosa | California | 95403 | — |
| Starling Physicians | New Britain | Connecticut | 06051 | — |
| George Washington University Medical Center | Washington D.C. | District of Columbia | 20037 | — |
| Central Florida Pulmonary Group, P.A. | Altamonte Springs | Florida | 32701 | — |
| Pulmonary, Critical Care & Sleep Disorders Institute of South Florida | Atlantis | Florida | 33462 | — |
| CTMD Research | Coconut Creek | Florida | 33063 | — |
| Life Arc Research Centers | Coral Gables | Florida | 33134 | — |
| Pulmonary Physicians of South Florida, LLC | Coral Springs | Florida | 33065 | — |
| SIMED Health, LLC | Gainesville | Florida | 32607 | — |
| National Research Institute | Hialeah | Florida | 33013 | — |
| 3Sync Research | Hialeah | Florida | 33016 | — |
| Zenith Clinical Research | Hollywood | Florida | 33024 | — |
| Multi-Specialty Research Associates, Inc. | Lake City | Florida | 32055 | — |
| 3Sync Research | Lake Worth | Florida | 33460 | — |
| Adtremed INC | Lutz | Florida | 33548 | — |
| Las Mias Research and Medical Center | Miami | Florida | 33144 | — |
| Monzon Clinical Trials | Miami | Florida | 33144 | — |
| Valencia Medical and Research Center | Miami | Florida | 33165 | — |
| Miami Pulmonary Specialists | Miami | Florida | 33173 | — |
| Florida Research Center, Inc. | Miami | Florida | 33174 | — |
| Charisma Medical and Research Center | Miami Lakes | Florida | 33014 | — |
| Adult Medicine of Lake County | Mt. Dora | Florida | 32757 | — |
| Central Florida Pulmonary Group, P.A. | Orlando | Florida | 32803 | — |
| Central Florida Pulmonary Group, P.A. | Orlando | Florida | 32825 | — |
| CTMD Research | Palm Springs | Florida | 33406 | — |
| Coastal Pulmonary and Critical Care, P.L.C. | St. Petersburg | Florida | 33704 | — |
| Adtremed Research Clinic | Tampa | Florida | 33607 | — |
| VICIS Clinical Research | Tampa | Florida | 33615 | — |
| Midtown OB/GYN North | Columbus | Georgia | 31901 | — |
| Pulmonary and Sleep Specialists of Northeast Georgia, PC | Dacula | Georgia | 30019 | — |
| DC Research Works | Marietta | Georgia | 30060 | — |
| Randomize Now, LLC | Peachtree City | Georgia | 30269 | — |
| Pulmonary and Sleep Specialists of Northeast Georgia, PC | Winder | Georgia | 30680 | — |
| Christie Clinic | Champaign | Illinois | 61822 | — |
| Eagle Clinical Research | Chicago | Illinois | 60621 | — |
| Hutchinson Clinic - North Waldron | Hutchinson | Kansas | 67502 | — |
| MedCorps Asthma and Pulmonary Specialists | Maysville | Kentucky | 41056 | — |
| Family Medicine Physicians | Hammond | Louisiana | 70403 | — |
| Willis-Knighton Cancer Center | Shreveport | Louisiana | 71103 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| HealthPartners Institute | Minneapolis | Minnesota | 55440 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Memorial Hospital at Gulfport | Gulfport | Mississippi | 39501 | — |
| Olive Branch Family Medical Center | Olive Branch | Mississippi | 38654 | — |
| Family Medical Clinic of North Mississippi | Southaven | Mississippi | 38672 | — |
| Branson Pulmonology and Sleep Medicine | Branson | Missouri | 65616 | — |
| Washington University School of Medicine/Barnes-Jewish Hospital | St Louis | Missouri | 63310 | — |
| Somnos Clinical Research | Lincoln | Nebraska | 68510 | — |
| Great Plains Health | North Platte | Nebraska | 69101 | — |
| Ocean Pulmonary Associates | Brick | New Jersey | 08724 | — |
| Ocean University Medical Center | Brick | New Jersey | 08724 | — |
| RespaCare | Bridgewater | New Jersey | 08807 | — |
| MedCorps Asthma and Pulmonary Specialists | Cape May Court House | New Jersey | 08210 | — |
| Pulmonary & Sleep Disorders of New Jersey | East Brunswick | New Jersey | 08816 | — |
| JFK University Medical Center | Edison | New Jersey | 08820 | — |
| Pulmonary Internists | Edison | New Jersey | 08820 | — |
| Pulmonary Specialists of North Jersey | Englewood | New Jersey | 07631 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| John Theurer Cancer Center at Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| MedCorps Asthma and Pulmonary Specialists | Linwood | New Jersey | 08221 | — |
| Pulmonary & Sleep Disorders of New Jersey | Monroe | New Jersey | 08831 | — |
| John Theurer Cancer Center at Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | — |
| Pulmonary Specialists of North Jersey | North Bergen | New Jersey | 07047 | — |
| Respiratory and Sleep Specialists, LLC | Princeton | New Jersey | 08540 | — |
| Riverview Medical Center | Red Bank | New Jersey | 07701 | — |
| North Jersey Pulmonary Associates | Ridgewood | New Jersey | 07450 | — |
| MedCorps Asthma and Pulmonary Specialists | Sewell | New Jersey | 08080 | — |
| Ocean Pulmonary Associates | Toms River | New Jersey | 08755 | — |
| Long Island Pulmonary and Sleep Medicine Associates | Hempstead | New York | 11550 | — |
| Long Island Pulmonary and Sleep Medicine Associates | Rockville Centre | New York | 11570 | — |
| Great Lakes Medical Research | Westfield | New York | 14787 | — |
| CTMD Research, Asheville | Asheville | North Carolina | 28804 | — |
| MacGregor Family Physicians, P.A. | Cary | North Carolina | 27518 | — |
| Durham VA Medical Center | Durham | North Carolina | 27705 | — |
| Clinical Research of Gastonia | Gastonia | North Carolina | 28054 | — |
| Peters Medical Research | High Point | North Carolina | 27262 | — |
| Piedmont Healthcare | Statesville | North Carolina | 28625 | — |
| Wilmington Health | Wilmington | North Carolina | 28401 | — |
| Lillestol Research, LLC | Fargo | North Dakota | 58104 | — |
| Pulmonology Associates Inc. | Broomall | Pennsylvania | 19008 | — |
| Advocare Pulmonary And Sleep Specialists | Exton | Pennsylvania | 19341 | — |
| Advocare Pulmonary And Sleep Specialists | Lansdale | Pennsylvania | 19446 | — |
| Pulmonology Associates Inc. | Paoli | Pennsylvania | 19301 | — |
| Advocare Pulmonary And Sleep Specialists | West Chester | Pennsylvania | 19380 | — |
| Pulmonology Associates Inc.Pulmonology Associates Inc. (Suite 108) | Wynnewood | Pennsylvania | 19096 | — |
| Pulmonology Associates Inc. | Wynnewood | Pennsylvania | 19096 | — |
| Berks Schuylkill Respiratory Specialists, Ltd. | Wyomissing | Pennsylvania | 19610 | — |
| Vista Clinical Research | Columbia | South Carolina | 29201 | — |
| The Jackson Clinic | Jackson | Tennessee | 38305 | — |
| Midsouth Independent Group | Memphis | Tennessee | 38104 | — |
| Midsouth Independent Group | Memphis | Tennessee | 38106 | — |
| Midsouth Independent Group | Memphis | Tennessee | 38114 | — |
| MidSouth Independent Group | Memphis | Tennessee | 38119 | — |
| Mid-South Pulmonary & Sleep Specialists PC | Memphis | Tennessee | 38157 | — |
| Peabody Internal Medicine Inc. | Millington | Tennessee | 38053 | — |
| Austin Regional Clinic | Austin | Texas | 78726 | — |
| Premier Family Physicians | Austin | Texas | 78735 | — |
| ARC Clinical Research at William Cannon | Austin | Texas | 78745 | — |
| Pulmonary Critical Care & Sleep Associates, P.A. | Conroe | Texas | 77304 | — |
| Horizon Clinical Research Group | Cypress | Texas | 77429 | — |
| Southwest Family Medicine Associates | Dallas | Texas | 75235 | — |
| El Paso Pulmonary Associates | El Paso | Texas | 79902 | — |
| Allure Heath at Mt. Olympus Medical Research | Friendswood | Texas | 77546 | — |
| Best Cancer Care & Hematology - Biopharma Informatic | Houston | Texas | 77089 | — |
| Huntsville Research Institute, LLC | Huntsville | Texas | 77340 | — |
| Vytalus Medical Group | Kingwood | Texas | 77339 | — |
| Covenant Health System/Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | 79410 | — |
| Wellness Clinical Research | McKinney | Texas | 75071 | — |
| PRX Research | Mesquite | Texas | 75149 | — |
| Oak Cliff Research | Richardson | Texas | 75081 | — |
| Sugar Lakes Family Practice, PA | Sugar Land | Texas | 77479 | — |
| Tidewater Physicians Multispecialty Group, P.C. | Williamsburg | Virginia | 23188 | — |
| Western Washington Medical Group, Inc | Everett | Washington | 98208 | — |
| The Vancouver Clinic | Vancouver | Washington | 98664 | — |
| CAMC Clinical Trials Center | Charleston | West Virginia | 25304 | — |
| Mayo Clinic Health System Eau Claire | Eau Claire | Wisconsin | 54703 | — |
| Mayo Clinic La Crosse | La Crosse | Wisconsin | 54601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05117840, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 6, 2026 · Synced Oct 31, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05117840 live on ClinicalTrials.gov.