A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)
Public ClinicalTrials.gov record NCT05122650. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, 12-week, Double-blind, Placebo-controlled, Randomized, Parallel Group, Multicenter Study of the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a 12-week, double-blind, placebo-controlled, randomized, parallel-group, multicenter study of the safety and efficacy of JZP385 in the treatment of adult participants with moderate to severe ET.
Study identification
- NCT ID
- NCT05122650
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 420 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 6, 2021 (Actual)
- Primary completion
- May 30, 2024 (Actual)
- Completion
- May 30, 2024 (Actual)
- Last update posted
- Jul 24, 2025
2021 – 2024
United States locations
- U.S. sites
- 41
- U.S. states
- 19
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University Of Alabama At Birmingham (Uab) | Birmingham | Alabama | 35233 | — |
| St. Joseph's Hospital and Medical Center (SJHMC) - Barrow Neurological Institute (BNI) - The Gregory W. Fulton ALS and Neuromuscular Disease Center | Phoenix | Arizona | 85013 | — |
| Arizona Neuroscience Research, LLC | Phoenix | Arizona | 85032 | — |
| Imaging Endpoints II, LLC | Scottsdale | Arizona | 85258 | — |
| Movement Disorders Center of Arizona | Scottsdale | Arizona | 85258 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| Pillar Clinical Research, LLC | Bentonville | Arkansas | 72712 | — |
| Woodland Research Northwest, LLC | Rogers | Arkansas | 72758 | — |
| The Parkinson's and Movement Disorder Institute | Fountain Valley | California | 92708 | — |
| Keck School of Medicine USC - Healthcare Consultation Center 2 (HCCII) | Los Angeles | California | 90033 | — |
| SC3 Research - Beverly | Los Angeles | California | 90048 | — |
| SC3 Research Pasadena | Pasadena | California | 91105 | — |
| Neurology of Central Florida Research Center | Altamonte Springs | Florida | 32714 | — |
| JEM Research Institute | Atlantis | Florida | 33462 | — |
| Parkinson's Disease And Movement Disorder Center Of Boca Raton | Boca Raton | Florida | 33486 | — |
| Innovative Research Of West Florida, Inc. | Clearwater | Florida | 33756 | — |
| Infinity Clinical Research, Llc | Hollywood | Florida | 33024 | — |
| Clinical Neuroscience Solutions, Inc. | Jacksonville | Florida | 33217 | — |
| Homestead Associates in Research, Inc. | Miami | Florida | 33032 | — |
| USF Carol and Frank Morsani Center for Advanced Healthcare | Tampa | Florida | 33612 | — |
| University of South Florida Parkinson's Disease and Movement Disorders Center | Tampa | Florida | 33613 | — |
| Neurotrials Research, Inc. | Atlanta | Georgia | 30328 | — |
| Brain Health Center, Emory University | Atlanta | Georgia | 30329 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96817 | — |
| Northwestern University - Feinberg School of Medicine - Parkinsonÿs Disease and Movement Disorders Center | Chicago | Illinois | 60611 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Louisville, Movement Disorder Clinic | Louisville | Kentucky | 40202 | — |
| QUEST Research Institute | Farmington Hills | Michigan | 48334 | — |
| University Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Dent Neurological Institute | Amherst | New York | 14226 | — |
| South Shore Neurology Associates, Inc. | Patchogue | New York | 11772 | — |
| University of Rochester Medical Center | Rochester | New York | 14618 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10314 | — |
| Duke University Health System | Durham | North Carolina | 27705 | — |
| American Clinical Research Institute LLC | Beavercreek | Ohio | 45432 | — |
| NeuroScience Research Center | Canton | Ohio | 44718 | — |
| Midwest Clinical Research Center | Dayton | Ohio | 45417 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Houston Methodist Hospital - Movement Disorders Clinic | Houston | Texas | 77030 | — |
| Booth Gardner Parkinson's Care Center | Kirkland | Washington | 98034 | — |
| Vaught Neurological Services, PLLC | Crab Orchard | West Virginia | 25827 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05122650, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 24, 2025 · Synced Nov 4, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05122650 live on ClinicalTrials.gov.