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Terminated Phase 3 Interventional Results available

Efficacy and Safety of Tolebrutinib (SAR442168) Tablets in Adult Participants With Generalized Myasthenia Gravis

ClinicalTrials.gov ID: NCT05132569

Public ClinicalTrials.gov record NCT05132569. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 5:11 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Tolebrutinib (SAR442168) in Adults With Generalized Myasthenia Gravis (MG)

Study identification

NCT ID
NCT05132569
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Sanofi
Industry
Enrollment
6 participants

Conditions and interventions

Interventions

  • Tolebrutininb Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 2, 2021
Primary completion
Feb 20, 2023
Completion
Feb 20, 2023
Last update posted
Sep 8, 2025

2021 – 2023

United States locations

U.S. sites
5
U.S. states
4
U.S. cities
5
Facility City State ZIP Site status
Georgetown University-Site Number:8400008 Washington D.C. District of Columbia 20007
SFM Clinical Research, LLC-Site Number:8400006 Boca Raton Florida 33487
University of South Florida Health- Morsani Center for Advanced Healthcare-Site Number:8400001 Tampa Florida 33612-6601
Harvard Medical School - Brigham and Women's Hospital-Site Number:8400004 Boston Massachusetts 02115
Neurology Center of San Antonio, PA-Site Number:8400009 San Antonio Texas 00000

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05132569, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 8, 2025 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05132569 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →