A Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Vaccine Boosters
Public ClinicalTrials.gov record NCT05137236. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2A, Randomized, Stratified, Observer-Blind Study to Evaluate the Immunogenicity and Safety of mRNA-1283 Vaccine Boosters for SARS-CoV-2
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main goal of Part A of this study is to assess the safety, reactogenicity, and immunogenicity of the study vaccine candidates. The main goal of Part B of this study is to assess the safety, reactogenicity, and immunogenicity of the mRNA-1283.529 booster vaccine candidate.
Study identification
- NCT ID
- NCT05137236
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 540 participants
Conditions and interventions
Conditions
Interventions
- mRNA-1283 Biological
- mRNA-1283.211 Biological
- mRNA-1273 Biological
- mRNA-1283.529 Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 6, 2021 (Actual)
- Primary completion
- Mar 23, 2023 (Actual)
- Completion
- Mar 23, 2023 (Actual)
- Last update posted
- Jul 17, 2025
2021 – 2023
United States locations
- U.S. sites
- 17
- U.S. states
- 13
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MedPharmics, LLC | Phoenix | Arizona | 85015-1105 | — |
| Research Centers of America | Hollywood | Florida | 33024-2709 | — |
| Precision Clinical Research | Sunrise | Florida | 33351-7311 | — |
| Tekton Research | Chamblee | Georgia | 30341 | — |
| MedPharmics | Metairie | Louisiana | 70006 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01655-0002 | — |
| Clinical Research Institute, Inc - CRN | Minneapolis | Minnesota | 55402-2700 | — |
| Meridian Clinical Research (Nebraska) | Lincoln | Nebraska | 68510 | — |
| MedPharmics, LLC. - Albuquerque | Albuquerque | New Mexico | 87102-3876 | — |
| Rochester Clinical Research, Inc. | Rochester | New York | 14609 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Meridian Clinical Research (Cincinnati) | Cincinnati | Ohio | 45246-2316 | — |
| Aventiv Research Inc | Columbus | Ohio | 43213-6517 | — |
| Coastal Carolina Research Center | North Charleston | South Carolina | 29405-4986 | — |
| ACRC Trials | Frisco | Texas | 75033-4135 | — |
| Ventavia Research Group | Houston | Texas | 77008 | — |
| Health Research of Hampton Roads Inc. | Newport News | Virginia | 23606-4537 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05137236, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 17, 2025 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05137236 live on ClinicalTrials.gov.