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Active, not recruiting Phase 3 Interventional

Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis

ClinicalTrials.gov ID: NCT05138133

Public ClinicalTrials.gov record NCT05138133. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:26 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicentre Randomized Double-Blind Placebo Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy and safety of IV antifrolumab in adult patients with Active Proliferative Lupus Nephritis

Study identification

NCT ID
NCT05138133
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
363 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 14, 2022
Primary completion
Feb 22, 2027
Completion
Oct 3, 2028
Last update posted
Jul 30, 2026

2022 – 2028

United States locations

U.S. sites
16
U.S. states
10
U.S. cities
16
Facility City State ZIP Site status
Research Site Glendale Arizona 85306
Research Site La Palma California 90623
Research Site Los Angeles California 90095
Research Site Upland California 91786
Research Site Plantation Florida 33324
Research Site Atlanta Georgia 30308
Research Site Louisville Kentucky 40202
Research Site Summit New Jersey 07901
Research Site Manhasset New York 11030
Research Site New York New York 10016
Research Site Winston-Salem North Carolina 27157
Research Site Middleburg Heights Ohio 44130
Research Site Colleyville Texas 76034
Research Site Edinburg Texas 78539
Research Site El Paso Texas 79902
Research Site Houston Texas 77054

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 148 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05138133, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 30, 2026 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05138133 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →