A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy
Public ClinicalTrials.gov record NCT05139602. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Safety and Efficacy of Lutikizumab (ABT-981) in Adult Subjects With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy: Amended Protocol to Include a Lutikizumab Open-Label Sub-study in Subjects Naïve to Biologic Therapy
Study identification
- NCT ID
- NCT05139602
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 210 participants
Conditions and interventions
Conditions
Interventions
- Lutikizumab Biological
- Placebo Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 27, 2021
- Primary completion
- Nov 30, 2027
- Completion
- Nov 30, 2027
- Last update posted
- Feb 12, 2026
2021 – 2027
United States locations
- U.S. sites
- 25
- U.S. states
- 13
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Dermatology Specialists /ID# 240641 | Phoenix | Arizona | 85006 | — |
| Mayo Clinic - Scottsdale /ID# 241030 | Scottsdale | Arizona | 85259-5452 | — |
| Burke Pharmaceutical Research /ID# 240811 | Hot Springs | Arkansas | 71913-6404 | — |
| UCSF Fresno /ID# 240903 | Fresno | California | 93701-2302 | — |
| Medderm Associates /ID# 240729 | San Diego | California | 92103 | — |
| Clinical Trials Research Institute /ID# 240642 | Thousand Oaks | California | 91320-2130 | — |
| CCD Research, PLLC /ID# 240728 | Cromwell | Connecticut | 06416-1745 | — |
| Skin Care Research Boca Raton /ID# 240758 | Boca Raton | Florida | 33486-2269 | — |
| Apex Clinical Trials /ID# 248558 | Brandon | Florida | 33511 | — |
| GSI Clinical Research, LLC /ID# 240901 | Margate | Florida | 33063 | — |
| Florida International Rsrch cr /ID# 240902 | Miami | Florida | 33173 | — |
| Park Avenue Dermatology, PA /ID# 240807 | Orange Park | Florida | 32073 | — |
| Duplicate_TruDerm Dermatology of Wellington /ID# 240780 | Wellington | Florida | 33449 | — |
| Dawes Fretzin, LLC /ID# 240701 | Indianapolis | Indiana | 46256 | — |
| Beth Israel Deaconess Medical Center /ID# 240683 | Boston | Massachusetts | 02215-5400 | — |
| Revival Research Institute, LLC /ID# 241020 | Troy | Michigan | 48084-3536 | — |
| MediSearch Clinical Trials /ID# 240810 | Saint Joseph | Missouri | 64506 | — |
| Washington University-School of Medicine /ID# 240797 | St Louis | Missouri | 63110 | — |
| Advanced Dermatology of the Midlands /ID# 249750 | Omaha | Nebraska | 68144-1105 | — |
| Duplicate_Skin Specialists, PC /ID# 240804 | Omaha | Nebraska | 68144 | — |
| Schweiger Dermatology, P.C. /ID# 240900 | New York | New York | 07044-2946 | — |
| Mount Sinai Doctors Dermatology /ID# 241588 | New York | New York | 10029-6504 | — |
| Montefiore Medical Center /ID# 240853 | The Bronx | New York | 10467 | — |
| Essential Medical Research, LLC /ID# 241807 | Tulsa | Oklahoma | 74137-2842 | — |
| Center for Clinical Studies - Houston (Binz) /ID# 240692 | Houston | Texas | 77004-8097 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05139602, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 12, 2026 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05139602 live on ClinicalTrials.gov.